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Folic acid conjugated PAMAM-modified mesoporous silica-coated superparamagnetic iron oxide nanoparticles for potential cancer therapy

dc.contributor.authorTabakoglu, O.
dc.contributor.authorZaim, M.
dc.contributor.authorSagir, T.
dc.contributor.authorHuysal, M.
dc.contributor.authorSenel, M.
dc.contributor.authorIsik, S.
dc.contributor.authorBurgucu, N.
dc.date.accessioned2023-02-21T07:26:51Z
dc.date.available2023-02-21T07:26:51Z
dc.identifier.citationSagir T., Huysal M., Senel M., Isik S., Burgucu N., Tabakoglu O., Zaim M., "Folic acid conjugated PAMAM-modified mesoporous silica-coated superparamagnetic iron oxide nanoparticles for potential cancer therapy", JOURNAL OF COLLOID AND INTERFACE SCIENCE, cilt.625, ss.711-721, 2022
dc.identifier.issn0021-9797
dc.identifier.otherav_068a14ee-a7f0-4d22-865b-15cccd1d50f9
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/185808
dc.identifier.urihttps://doi.org/10.1016/j.jcis.2022.06.069
dc.description.abstractIn this study, novel folate-receptor-targeted polyamidoamine (PAMAM) dendrimer functional mesoporous silica-coated magnetic nanoparticles were prepared for drug delivery agents for photodynamic therapy applications. The surface of the magnetic nanoparticles was coated with mesoporous silica (M-MSN). The M-MSN nanoparticles were functionalized with siloxane-cored PAMAM dendrons (generation 1 to 3). The surface of the M-MSN-PAMAM nanocarriers was targeted with folic acid. Indocyanine green (ICG) a near-infrared dye was loaded in the M-MSN-PAMAM nanocarriers and the photodynamic therapy efficiency of the drug-loaded nanocarriers was evaluated on MCF-7 cells.
dc.language.isoeng
dc.subjectFiziksel ve Teorik Kimya
dc.subjectKimya
dc.subjectTemel Bilimler (SCI)
dc.subjectFizikokimya
dc.subjectTemel Bilimler
dc.subjectYüzeyler ve Arayüzler
dc.subjectYüzeyler, Kaplamalar ve Filmler
dc.subjectKİMYA, FİZİKSEL
dc.subjectKimya (çeşitli)
dc.subjectGenel Kimya
dc.subjectFizik Bilimleri
dc.titleFolic acid conjugated PAMAM-modified mesoporous silica-coated superparamagnetic iron oxide nanoparticles for potential cancer therapy
dc.typeMakale
dc.relation.journalJOURNAL OF COLLOID AND INTERFACE SCIENCE
dc.contributor.departmentPim Grup Cosmet Consultancy , ,
dc.identifier.volume625
dc.identifier.startpage711
dc.identifier.endpage721
dc.contributor.firstauthorID4075971


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