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dc.contributor.authorPASTACI ÖZSOBACI, NURAL
dc.contributor.authorKalkan, M. T.
dc.contributor.authorYilmaz, T.
dc.contributor.authorOzcelik, D.
dc.contributor.authorDuzgun Ergun, D.
dc.date.accessioned2022-02-18T11:28:04Z
dc.date.available2022-02-18T11:28:04Z
dc.identifier.citationDuzgun Ergun D., PASTACI ÖZSOBACI N., Yilmaz T., Ozcelik D., Kalkan M. T. , "Zinc affects nuclear factor kappa b and DNA methyltransferase activity in C3H cancer fibroblast cells induced by a 2100 MHz electromagnetic field", ELECTROMAGNETIC BIOLOGY AND MEDICINE, 2022
dc.identifier.issn1536-8378
dc.identifier.othervv_1032021
dc.identifier.otherav_fbb05efa-6ebd-4e74-9dfb-2b4e3b5a8bcd
dc.identifier.urihttp://hdl.handle.net/20.500.12627/181266
dc.identifier.urihttps://doi.org/10.1080/15368378.2021.2019760
dc.description.abstractThe use of mobile phones is becoming widespread with the development of technology, and as a result, its effects on human health are becoming more and more important every day. Studies have reported that the electromagnetic field (EMF) emitted by mobile phones may have adverse effects on the biological systems. In order to evaluate the effect of zinc (Zn) on C3H cancer fibroblast cells exposed to 2100 MHz EMF, we analyzed cell viability%, nuclear factor kappa b (NF-kappa B) and DNA methyltransferase (DNMT) activities. Cells were divided to following groups: Control, sham control, 2100 MHz EMF, 50 mu M Zn + 2100 MHz EMF, 100 mu M Zn + 2100 MHz EMF, and 200 mu M Zn + 2100 MHz EMF for 2 h. We measurement cell viability, NF-kappa B and DNMT activities. There was increased cell viability % in the 2100 MHz EMF group compared to the control group, while the cell viability % was decreased in the 50, 100 and 200 mu M Zn + 2100 MHz EMF groups compared to 2100 MHz EMF. NF kappa B and DNMT activities were a significant increase in the 2100 MHz EMF group compared to the control group, although were statistically decreased in the 50, 100 and 200 mu M Zn + 2100 MHz EMF groups compared to the 2100 MHz EMF group. Our results demonstrate that 2100 MHz EMF exposure in cancer fibroblast cells induce NF-kappa B and DNMT activities, whereas zinc supplementation reduce NF-kappa B and DNMT activities-induced 2100 MHz EMF.
dc.language.isoeng
dc.subjectBiyofizik
dc.subjectBiyokimya
dc.subjectTıbbi Biyoloji
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectBiophysics
dc.subjectBiochemistry (medical)
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectSağlık Bilimleri
dc.subjectBİYOFİZİK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBiyoloji ve Biyokimya
dc.subjectBİYOLOJİ
dc.subjectTemel Tıp Bilimleri
dc.subjectTıp
dc.titleZinc affects nuclear factor kappa b and DNA methyltransferase activity in C3H cancer fibroblast cells induced by a 2100 MHz electromagnetic field
dc.typeMakale
dc.relation.journalELECTROMAGNETIC BIOLOGY AND MEDICINE
dc.contributor.departmentİstanbul Aydın Üniversitesi , ,
dc.contributor.firstauthorID3060652


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