dc.contributor.author | Leblebicioglu, H | |
dc.contributor.author | Haznedaroglu, I | |
dc.contributor.author | Turgut, M | |
dc.contributor.author | Sunbul, M | |
dc.contributor.author | Bayirli, D | |
dc.contributor.author | BİLGE, Ahmet Kaya | |
dc.date.accessioned | 2022-02-18T11:20:05Z | |
dc.date.available | 2022-02-18T11:20:05Z | |
dc.date.issued | 2002 | |
dc.identifier.citation | Turgut M., Sunbul M., Bayirli D., BİLGE A. K. , Leblebicioglu H., Haznedaroglu I., "Thrombocytopenia complicating the clinical course of leptospiral infection", JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, cilt.30, sa.5, ss.535-540, 2002 | |
dc.identifier.issn | 0300-0605 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_eb13c823-c070-4469-959e-cf8a676eb367 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/180950 | |
dc.identifier.uri | https://doi.org/10.1177/147323000203000511 | |
dc.description.abstract | Leptospirosis can present with a wide clinical spectrum, and haematological manifestations are often apparent. We retrospectively analysed platelet counts in 49 patients with leptospirosis. Forty-three patients (87.8%) had thrombocytopenia. Mean baseline platelet counts rose from 69 x 10(9)/1 to 151 x 10(9)/1 following treatment. Haemorrhagic episodes were observed in 11 patients. Platelet nadir was 29 x 10(9)/1 in the group experiencing bleeding and 64 x 10(9)/1 in the remainder. Six patients died due to bleeding and one due to sepsis. Thirty-six patients (73.5%) had acute renal failure; their mean platelet count was 46 x 10(9)/1. Liver enzyme levels were elevated in all patients. Thrombocyte count, liver enzyme levels and bilirubin levels were significantly correlated. Forty-three (87.8%) patients showed signs of sepsis; mean thrombocyte count was 46 x 10(9)/1 in these patients, and 133 x 10(9)/1 in those without sepsis. Multiple organ involvement and fulminant disease is usually associated with renal failure and/or thrombocytopenia in leptospirosis. | |
dc.language.iso | eng | |
dc.subject | Drug Guides | |
dc.subject | TIP, ARAŞTIRMA VE DENEYSEL | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | FARMAKOLOJİ VE ECZACILIK | |
dc.subject | Farmakoloji ve Toksikoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Life Sciences | |
dc.subject | Health Sciences | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Pharmacology | |
dc.subject | General Pharmacology, Toxicology and Pharmaceutics | |
dc.subject | Pharmacology, Toxicology and Pharmaceutics (miscellaneous) | |
dc.subject | Reviews and References (medical) | |
dc.subject | Pharmacology (medical) | |
dc.subject | Research and Theory | |
dc.subject | Pharmacy | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Tıbbi Ekoloji ve Hidroklimatoloji | |
dc.subject | Eczacılık | |
dc.subject | Temel Eczacılık Bilimleri | |
dc.title | Thrombocytopenia complicating the clinical course of leptospiral infection | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | |
dc.contributor.department | , , | |
dc.identifier.volume | 30 | |
dc.identifier.issue | 5 | |
dc.identifier.startpage | 535 | |
dc.identifier.endpage | 540 | |
dc.contributor.firstauthorID | 3372145 | |