dc.contributor.author | Reni, Gianluigi | |
dc.contributor.author | Miyakoshi, Makoto | |
dc.contributor.author | Benasich, April A. | |
dc.contributor.author | Bianchi, Anna Maria | |
dc.contributor.author | Piazza, Caterina | |
dc.contributor.author | Cantiani, Chiara | |
dc.contributor.author | Akalin-Acar, Zeynep | |
dc.contributor.author | Makeig, Scott | |
dc.date.accessioned | 2022-02-18T11:14:41Z | |
dc.date.available | 2022-02-18T11:14:41Z | |
dc.identifier.citation | Piazza C., Cantiani C., Akalin-Acar Z., Miyakoshi M., Benasich A. A. , Reni G., Bianchi A. M. , Makeig S., "ICA-derived cortical responses indexing rapid multi-feature auditory processing in six-month-old infants", NEUROIMAGE, cilt.133, ss.75-87, 2016 | |
dc.identifier.issn | 1053-8119 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_e145fe3c-4448-4419-a040-ae9f51c96ed9 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/180726 | |
dc.identifier.uri | https://doi.org/10.1016/j.neuroimage.2016.02.060 | |
dc.description.abstract | The abilities of infants to perceive basic acoustic differences, essential for language development, can be studied using auditory event-related potentials (ERPs). However, scalp-channel averaged ERPs sum volume-conducted contributions from many cortical areas, reducing the functional specificity and interpretability of channel-based ERP measures. This study represents the first attempt to investigate rapid auditory processing in infancy using independent component analysis (ICA), allowing exploration of source-resolved ERP dynamics and identification of ERP cortical generators. Here, we recorded 60-channel EEG data in 34 typically developing 6-month-old infants during a passive acoustic oddball paradigm presenting 'standard' tones interspersed with frequency-or duration-deviant tones. ICA decomposition was applied to single-subject EEG data. The best-fitting equivalent dipole or bilaterally symmetric dipole pair was then estimated for each resulting independent component (IC) process using a four-layer infant head model. Similar brain-source ICs were clustered across subjects. Results showed ERP contributions from auditory cortex and multiple extra-auditory cortical areas (often, bilaterally paired). Different cortical source combinations contributed to the frequency-and duration-deviant ERP peak sequences. For ICs in an ERP-dominant source cluster located in or near the mid-cingulate cortex, source-resolved frequency-deviant response N2 latency and P3 amplitude at 6 months-of-age predicted vocabulary size at 20 months-of-age. The same measures for scalp channel F6 (though not for other frontal channels) showed similar but weaker correlations. These results demonstrate the significant potential of ICA analyses to facilitate a deeper understanding of the neural substrates of infant sensory processing. (C) 2016 Elsevier Inc. All rights reserved. | |
dc.language.iso | eng | |
dc.subject | Radiology, Nuclear Medicine and Imaging | |
dc.subject | Radiological and Ultrasound Technology | |
dc.subject | Physical Sciences | |
dc.subject | Life Sciences | |
dc.subject | Health Sciences | |
dc.subject | Human-Computer Interaction | |
dc.subject | NEUROSCIENCES | |
dc.subject | Sinirbilim ve Davranış | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | NÖRO-GÖRÜNTÜLEME | |
dc.subject | RADYOLOJİ, NÜKLEER TIP ve MEDİKAL GÖRÜNTÜLEME | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Nükleer Tıp | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Developmental Neuroscience | |
dc.subject | Cellular and Molecular Neuroscience | |
dc.subject | Cognitive Neuroscience | |
dc.subject | General Neuroscience | |
dc.subject | Neuroscience (miscellaneous) | |
dc.subject | Sensory Systems | |
dc.title | ICA-derived cortical responses indexing rapid multi-feature auditory processing in six-month-old infants | |
dc.type | Makale | |
dc.relation.journal | NEUROIMAGE | |
dc.contributor.department | Polytechnic University of Milan , , | |
dc.identifier.volume | 133 | |
dc.identifier.startpage | 75 | |
dc.identifier.endpage | 87 | |
dc.contributor.firstauthorID | 3384307 | |