dc.contributor.author | Middleton, D. | |
dc.contributor.author | Gourraud, P. A. | |
dc.contributor.author | Meenagh, A. | |
dc.contributor.author | Sleator, C. | |
dc.contributor.author | Diler, A. S. | |
dc.date.accessioned | 2021-03-02T23:18:08Z | |
dc.date.available | 2021-03-02T23:18:08Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Middleton D., Diler A. S. , Meenagh A., Sleator C., Gourraud P. A. , "Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia", TISSUE ANTIGENS, cilt.73, sa.6, ss.553-560, 2009 | |
dc.identifier.issn | 0001-2815 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_11aaeee0-67e1-4b76-9e14-b1f5429f9507 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/17340 | |
dc.identifier.uri | https://doi.org/10.1111/j.1399-0039.2009.01235.x | |
dc.description.abstract | We have analysed the frequency of killer immunoglobulin-like receptors (KIR) in cohorts of patients from Turkey with acute lymphocyte leukaemia (n = 52), acute myeloid leukaemia (n = 54) and chronic myeloid leukaemia (CML) (n = 52) and compared the results with 154 controls. We also examined the frequencies of human leucocyte antigen (HLA)-C groups, -Bw4, -Bw6 and where appropriate the combination of the KIR gene and its ligand. We found several statistically significant results between the patients and the controls. We proposed a model in CML of protection via KIR2DL2 and/or KIR2DS2 with the presence of the ligand HLA-C1 group and susceptibility via HLA-Bw4 homozygosity (i.e. absence of HLA-Bw6). | |
dc.language.iso | eng | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Biyokimya | |
dc.subject | Histoloji-Embriyoloji | |
dc.subject | Cerrahi Tıp Bilimleri | |
dc.subject | Patoloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | Temel Bilimler | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Biyoloji ve Biyokimya | |
dc.subject | PATOLOJİ | |
dc.subject | İmmünoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | HÜCRE BİYOLOJİSİ | |
dc.title | Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia | |
dc.type | Makale | |
dc.relation.journal | TISSUE ANTIGENS | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 73 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 553 | |
dc.identifier.endpage | 560 | |
dc.contributor.firstauthorID | 192565 | |