dc.contributor.author | KAYA, EMİN | |
dc.contributor.author | Altuntas, Fevzi | |
dc.contributor.author | Hindilerden, Ipek Yonal | |
dc.contributor.author | BERBER, İLHAMİ | |
dc.contributor.author | Ulas, Turgay | |
dc.contributor.author | Batgi, Hikmettullah | |
dc.contributor.author | Dal, Mehmet Sinan | |
dc.contributor.author | ERKURT, MEHMET ALİ | |
dc.contributor.author | KUKU, İRFAN | |
dc.contributor.author | Kurtoglu, Erdal | |
dc.date.accessioned | 2021-12-10T11:41:19Z | |
dc.date.available | 2021-12-10T11:41:19Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Batgi H., Dal M. S. , ERKURT M. A. , KUKU İ., Kurtoglu E., Hindilerden I. Y. , KAYA E., BERBER İ., Ulas T., Altuntas F., "Extracorporeal photopheresis in the treatment of acute graft-versus-host disease: A multicenter experience", TRANSFUSION AND APHERESIS SCIENCE, cilt.60, sa.5, 2021 | |
dc.identifier.issn | 1473-0502 | |
dc.identifier.other | av_8e78e0bb-6a6b-4d5d-af7b-ff6689b730f8 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/172419 | |
dc.identifier.uri | https://doi.org/10.1016/j.transci.2021.103242 | |
dc.description.abstract | Background and objectives: Extracorporeal photopheresis (ECP) is one of the second-line treatment strategies in steroid-refractory acute graft-versus-host disease (aGvHD). We aimed to share our multicenter experience using ECP in our steroid-refractory aGvHD patients. Materials and methods: A retrospective observational series of 75 aGvHD patients from 4 transplant centers were analyzed. All ECP procedures were performed with the off-line system. All patients received ECP as second-line therapy. Results: 74.7 % of aGvHD patients were grade 3 or 4. The overall response rate was 42.7 % (32/75) in aGvHD including 17 complete responses (22.7 %). Median follow-up was 6 months (range, 1-68). Median overall survival (OS) was 5 months for non-responders and 68 months for responders (p < 0.001). Twenty-seven (36 %) patients are alive, and 48 (64 %) patients have died. Conclusions: Early initiated ECP could be an effective treatment alternative in patients with steroid-refractory aGvHD. | |
dc.language.iso | eng | |
dc.subject | Hematology | |
dc.subject | Health Sciences | |
dc.subject | İç Hastalıkları | |
dc.subject | Hematoloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | HEMATOLOJİ | |
dc.title | Extracorporeal photopheresis in the treatment of acute graft-versus-host disease: A multicenter experience | |
dc.type | Makale | |
dc.relation.journal | TRANSFUSION AND APHERESIS SCIENCE | |
dc.contributor.department | University of Health Sciences Turkey , , | |
dc.identifier.volume | 60 | |
dc.identifier.issue | 5 | |
dc.contributor.firstauthorID | 2740682 | |