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dc.contributor.authorOzbalak, Murat
dc.contributor.authorMedetalibeyoglu, Alpay
dc.contributor.authorAksoy, Elif
dc.contributor.authorCagatay, Atahan
dc.contributor.authorErelel, Mustafa
dc.contributor.authorGül, Ahmet
dc.contributor.authorEsen, Figen
dc.contributor.authorYavuz, Serap Simsek
dc.contributor.authorAlkac, Ummuhan Isoglu
dc.contributor.authorTukek, Tufan
dc.contributor.authorKose, Murat
dc.contributor.authorBesisik, Sevgi
dc.contributor.authorTor, Yavuz Burak
dc.contributor.authorSenkal, Naci
dc.date.accessioned2021-12-10T11:33:10Z
dc.date.available2021-12-10T11:33:10Z
dc.date.issued2021
dc.identifier.citationOzbalak M., Besisik S., Tor Y. B. , Medetalibeyoglu A., Kose M., Senkal N., Aksoy E., Cagatay A., Erelel M., Gül A., et al., "Initial complete blood count score and predicting disease progression in COVID-19 patients", AMERICAN JOURNAL OF BLOOD RESEARCH, cilt.11, sa.1, ss.77-83, 2021
dc.identifier.otherav_850e259f-1da2-434f-a0a6-f7f8ffb2b8c9
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/172122
dc.description.abstractIntroduction: Coronavirus has caused a pandemic since it was first detected in Wuhan in December 2019. The mortality rate is high in moderate and severe cases. Our study aimed to screen the CBC parameters as a useful predictive factor for COVID-19 resulting in critical illness. Methods: A total of 285 patients with positive PCR results were analyzed. The median age was 55 (24-90), and 64.2% of patients were male. Sixty-eight percent of cases were hospitalized with moderate, 32% with severe disease at initial admission. Results: We found that lymphocyte count 6, and platelet to lymphocyte ratio (PLR) >350 were predictive of the outcome. We scored our cohort 0-3 for these three parameters. Patients with a score of 2-3 were more likely to have progressive disease, anti-cytokine treatment, intensive care admission, intubation, and death, compared to patients with a score of 0-1. Additionally, they tended to be hospitalized for longer (median 11.5 days, mean 15.6), compared to those with a score 0 or 1 (median 9 days, mean 11.3). Twenty-eight of 38 cases with scores of 2-3 were discharged (73.6%), whereas the rate was 89% for patients with a score of 0-1 (P=0.009). Conclusion: Based on the absolute lymphocyte count (6, PLR >350), our three-parameter score was able to predict disease progression, and the likelihood of anti-cytokine treatment, intubation, and death. We think that COVID-19 patients presenting with moderate to severe pneumonia, and having scores of 2 or 3 on our scale, should be closely monitored and robustly supported.
dc.language.isoeng
dc.subjectResearch and Theory
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectReviews and References (medical)
dc.subjectHealth Sciences
dc.titleInitial complete blood count score and predicting disease progression in COVID-19 patients
dc.typeMakale
dc.relation.journalAMERICAN JOURNAL OF BLOOD RESEARCH
dc.contributor.departmentİstanbul Üniversitesi , İstanbul Tıp Fakültesi , Dahili Tıp Bilimleri Bölümü
dc.identifier.volume11
dc.identifier.issue1
dc.identifier.startpage77
dc.identifier.endpage83
dc.contributor.firstauthorID2605526


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