dc.contributor.author | Uysal, Betul Borku | |
dc.contributor.author | Yavuzer, Serap | |
dc.contributor.author | Islamoglu, Mehmet Sami | |
dc.contributor.author | Ikitimur, Hande | |
dc.contributor.author | YAVUZER, Hakan | |
dc.contributor.author | Bag Soytas, Rabia | |
dc.contributor.author | Cengiz, Mahir | |
dc.date.accessioned | 2021-12-10T10:52:07Z | |
dc.date.available | 2021-12-10T10:52:07Z | |
dc.identifier.citation | Bag Soytas R., Cengiz M., Islamoglu M. S. , Uysal B. B. , Ikitimur H., YAVUZER H., Yavuzer S., "Does the COVID-19 seroconversion in older adults resemble the young?", JOURNAL OF MEDICAL VIROLOGY, 2021 | |
dc.identifier.issn | 0146-6615 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_590d468d-3786-40be-b287-ebcaa85c653e | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/170740 | |
dc.identifier.uri | https://doi.org/10.1002/jmv.27106 | |
dc.description.abstract | High antibody titers have been found to correlate with the severity of coronavirus disease 2019 (COVID-19) disease. Therefore, antibody titers may be higher in older adults, whose disease is known to have a more severe course than younger ones. This study aimed to compare the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) antibody level in the reverse transcription-polymerase chain reaction (RT-PCR) to test positive older adults with young. Patients aged >= 18 with positive RT-PCR and checked serum IgG antibodies between November 1, 2020 and January 13, 2021 were included. The IgG antibody levels and the time between RT-PCR positivity with the antibody levels were recorded. A total of 1071 patients were divided into two groups as Group 1 = 60 years old (n = 169). The SARS-CoV-2 IgG antibody titers were higher in Group 2 (p = 0.001). This height was present in the first 3 months after positive RT-PCR. While the antibody titers were compared by dividing Group 2 into the three groups according to age ranges (60-69, 70-79, and >= 80 years), the antibody titer was higher in >= 80 years patients (p = 0.044). High COVID-19 IgG antibody levels may be associated with the severity of the disease. Also, the humoral immunity advantage was seen in the first 3 months in the older patients, which suggests that older adults with COVID-19 may develop reinfection in the long term. | |
dc.language.iso | eng | |
dc.subject | Viroloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | General Immunology and Microbiology | |
dc.subject | Immunology | |
dc.subject | Virology | |
dc.subject | Life Sciences | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Mikrobiyoloji ve Klinik Mikrobiyoloji | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | İmmünoloji | |
dc.subject | VİROLOJİ | |
dc.title | Does the COVID-19 seroconversion in older adults resemble the young? | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF MEDICAL VIROLOGY | |
dc.contributor.department | İstanbul Üniversitesi-Cerrahpaşa , , | |
dc.contributor.firstauthorID | 2639843 | |