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The effect of genetic polymorphisms of cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on drug-resistant epilepsy in Turkish children

dc.contributor.authorUnal, Selin
dc.contributor.authorYesil, Gözde
dc.contributor.authorGuven, Mehmet
dc.contributor.authorSeven, Mehmet
dc.contributor.authorBatar, Bahadir
dc.contributor.authorYuksel, Adnan
dc.date.accessioned2021-03-06T21:13:45Z
dc.date.available2021-03-06T21:13:45Z
dc.date.issued2014
dc.identifier.citationSeven M., Batar B., Unal S., Yesil G., Yuksel A., Guven M., "The effect of genetic polymorphisms of cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on drug-resistant epilepsy in Turkish children", Molecular Diagnosis and Therapy, cilt.18, ss.229-236, 2014
dc.identifier.issn1177-1062
dc.identifier.othervv_1032021
dc.identifier.otherav_fdbe988a-39eb-4653-9abc-727c88992b1a
dc.identifier.urihttp://hdl.handle.net/20.500.12627/165986
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84897399856&origin=inward
dc.identifier.urihttps://doi.org/10.1007/s40291-013-0078-8
dc.description.abstractDespite the availability of several antiepileptic drugs, drug resistance remains one of the major challenges in epilepsy therapy. Genetic factors are known to play a significant role in the prognosis and treatment of epilepsy. The aim of this study was to determine the frequencies of alleles for CYP2C9, CYP2C19, and CYP2D6 genes in Turkish children with epilepsy, and to investigate the relationship between the genetic polymorphism of these genes with multiple drug resistance in epilepsy patients.
dc.language.isoeng
dc.subjectTıbbi Genetik
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectGENETİK VE HAYAT
dc.titleThe effect of genetic polymorphisms of cytochrome P450 CYP2C9, CYP2C19, and CYP2D6 on drug-resistant epilepsy in Turkish children
dc.typeMakale
dc.relation.journalMolecular Diagnosis and Therapy
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume18
dc.identifier.issue2
dc.identifier.startpage229
dc.identifier.endpage236
dc.contributor.firstauthorID14904


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