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The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy

dc.contributor.authorOzkaynakci, Aydan
dc.contributor.authorAker, Rezzan Gulhan
dc.contributor.authorGÖREN, MEHMET ZAFER
dc.contributor.authorGulcebi, Medine Idrizoglu
dc.contributor.authorOzkara, Cigdem
dc.contributor.authorOnat, Filiz Yilmaz
dc.date.accessioned2021-03-06T21:13:29Z
dc.date.available2021-03-06T21:13:29Z
dc.identifier.citationGulcebi M. I. , Ozkaynakci A., GÖREN M. Z. , Aker R. G. , Ozkara C., Onat F. Y. , "The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy", EPILEPSY RESEARCH, cilt.95, ss.1-8, 2011
dc.identifier.issn0920-1211
dc.identifier.othervv_1032021
dc.identifier.otherav_fdb804c7-8b15-445c-a769-1dd16218bbbe
dc.identifier.urihttp://hdl.handle.net/20.500.12627/165971
dc.identifier.urihttps://doi.org/10.1016/j.eplepsyres.2011.01.016
dc.description.abstractLamotrigine (LTG) which has a widespread use in epilepsy treatment as an antiepileptic agent is metabolized by UDP-glucuronosyl transferase (UGT) enzymes. In this study, single nucleotide polymorphisms, P24T and L48V, of the UGT1A4 enzyme have been investigated in a Turkish population of patients with epilepsy (n=131) by comparing serum levels of LTG of wild type and polymorphic subjects.
dc.language.isoeng
dc.subjectNöroloji
dc.subjectKLİNİK NEUROLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.titleThe relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy
dc.typeMakale
dc.relation.journalEPILEPSY RESEARCH
dc.contributor.departmentMarmara Üniversitesi , ,
dc.identifier.volume95
dc.identifier.startpage1
dc.identifier.endpage8
dc.contributor.firstauthorID29528


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