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A triterpene oleanolic acid conjugate with 3-hydroxyflavone derivative as a new membrane probe with two-color ratiometric response

dc.contributor.authorDuportail, G
dc.contributor.authorDemchenko, AP
dc.contributor.authorKlymchenko, AS
dc.contributor.authorOncul, S
dc.contributor.authorTopcu, G
dc.contributor.authorTurkmen, Z
dc.date.accessioned2021-03-06T21:00:42Z
dc.date.available2021-03-06T21:00:42Z
dc.date.issued2005
dc.identifier.citationTurkmen Z., Klymchenko A., Oncul S., Duportail G., Topcu G., Demchenko A., "A triterpene oleanolic acid conjugate with 3-hydroxyflavone derivative as a new membrane probe with two-color ratiometric response", JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, cilt.64, ss.1-18, 2005
dc.identifier.issn0165-022X
dc.identifier.othervv_1032021
dc.identifier.otherav_fcc876f2-6464-48ca-979a-3fc7d283948a
dc.identifier.urihttp://hdl.handle.net/20.500.12627/165414
dc.identifier.urihttps://doi.org/10.1016/j.jbbm.2005.03.008
dc.description.abstractWe report on the synthesis by coupling of a triterpenoid oleanolic acid with 4'-diethylamino-3-hydroxyflavone (FE) to produce an environment-sensitive biomembrane probe with two-band ratiometric response in fluorescence emission. The synthesized compound (probe FOT) was tested in a series of model solvents and demonstrated the response to solvent polarity and intermolecular hydrogen bonding very similar to that of parent probe FE. Meantime when incorporated into lipid bilayer membranes, it showed new features differing in response between lipids of different surface charges as well as between glycerophospholipids and sphingomyelin.
dc.language.isoeng
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyofizik
dc.subjectBiyokimya
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectBİYOFİZİK
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBiyoloji ve Biyokimya
dc.subjectBİYOKİMYASAL ARAŞTIRMA YÖNTEMLERİ
dc.titleA triterpene oleanolic acid conjugate with 3-hydroxyflavone derivative as a new membrane probe with two-color ratiometric response
dc.typeMakale
dc.relation.journalJOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS
dc.contributor.department, ,
dc.identifier.volume64
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.endpage18
dc.contributor.firstauthorID175639


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