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Embryo viability indexing using Raman spectroscopy of spent culture media

dc.contributor.authorSag, Fatih
dc.contributor.authorParlatan, Ugur
dc.contributor.authorYumru, Harika
dc.contributor.authorBulgurcuoglu, Sibel
dc.contributor.authorBastu, Ercan
dc.contributor.authorBaşar, Günay
dc.contributor.authorBavili, Nima
dc.date.accessioned2021-03-06T20:50:46Z
dc.date.available2021-03-06T20:50:46Z
dc.date.issued2016
dc.identifier.citationParlatan U., Başar G., Bavili N., Yumru H., Sag F., Bulgurcuoglu S., Bastu E., "Embryo viability indexing using Raman spectroscopy of spent culture media", SPECTROSCOPY LETTERS, cilt.49, ss.458-463, 2016
dc.identifier.issn0038-7010
dc.identifier.otherav_fc076354-0bd9-418d-8ea9-b0fd973686a6
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/164959
dc.identifier.urihttps://doi.org/10.1080/00387010.2016.1198814
dc.description.abstractEmbryo viability quantification is an important topic for in vitro fertilization researchers. This study suggests Raman spectroscopy as a candidate method to find an objective measure of embryo viability. Raman spectra of 31 spent embryo culture samples (16 nonpregnant, 15 pregnant) from 31 patients were analyzed with band component analysis. The band area ratio of 902 to 943 cm 1 was found to be the most discriminatory. These bands are related to glutamine, glycine, proline, aspartic acid, and valine. According to the pregnancy outcome the sensitivity and specificity of Raman analysis were found to be 93% and 77%, respectively.
dc.language.isoeng
dc.subjectTemel Bilimler (SCI)
dc.subjectSpektroskopi
dc.subjectSPEKTROSKOPİ
dc.subjectKimya
dc.subjectFizikokimya
dc.subjectTemel Bilimler
dc.titleEmbryo viability indexing using Raman spectroscopy of spent culture media
dc.typeMakale
dc.relation.journalSPECTROSCOPY LETTERS
dc.contributor.departmentİstanbul Teknik Üniversitesi , Fen-Edebiyat ,
dc.identifier.volume49
dc.identifier.issue7
dc.identifier.startpage458
dc.identifier.endpage463
dc.contributor.firstauthorID227930


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