Show simple item record

dc.contributor.authorTas, Faruk
dc.contributor.authorDuranyildiz, Derya
dc.contributor.authorKarabulut, Senem
dc.date.accessioned2021-03-06T20:31:11Z
dc.date.available2021-03-06T20:31:11Z
dc.identifier.citationTas F., Karabulut S., Duranyildiz D., "Clinical significance of serum epithelial cell adhesion molecule (EPCAM) levels in patients with lung cancer", MOLECULAR AND CELLULAR BIOCHEMISTRY, cilt.396, ss.307-312, 2014
dc.identifier.issn0300-8177
dc.identifier.othervv_1032021
dc.identifier.otherav_fa8c0331-35fa-4cd2-9b00-75da9c8f897e
dc.identifier.urihttp://hdl.handle.net/20.500.12627/164051
dc.identifier.urihttps://doi.org/10.1007/s11010-014-2167-3
dc.description.abstractCellular adhesion molecules might be good markers in some types of malignant tumors, thus providing useful information in diagnosis and prognosis. The objective of this study was to determine the clinical significance of the serum levels of epithelial cell adhesion molecule (EPCAM) in lung cancer patients. One hundred and thirty lung cancer patients were enrolled in this study. Serum EPCAM levels were determined by the solid-phase sandwich ELISA method. Age- and sex-matched 34 healthy controls were included in the analysis. The median age was 58 years, ranging 35-80 years. The majority of the patients had NSCLC (83.8 %) and stage IV disease (60.8 %). There was no significant difference in the serum EPCAM levels between lung cancer patients and healthy controls (p = 0.16). Moreover, known clinical variables including age of patient, gender, histology, stage of disease, and response to chemotherapy were not found to be correlated with serum EPCAM concentrations (p > 0.05). Similarly, no prognostic role was found for outcome (1-year survival rate 62 vs. 65.1 %, p = 0.89). In conclusion, serum EPCAM concentrations have no diagnostic, predictive, and prognostic roles in lung cancer patients.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectHÜCRE BİYOLOJİSİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Tıp Bilimleri
dc.subjectHistoloji-Embriyoloji
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.titleClinical significance of serum epithelial cell adhesion molecule (EPCAM) levels in patients with lung cancer
dc.typeMakale
dc.relation.journalMOLECULAR AND CELLULAR BIOCHEMISTRY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume396
dc.identifier.startpage307
dc.identifier.endpage312
dc.contributor.firstauthorID33389


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record