dc.contributor.author | Akcay, T | |
dc.contributor.author | Kayali, R | |
dc.contributor.author | Colgar, U | |
dc.contributor.author | Oral, E | |
dc.contributor.author | Cakatay, U | |
dc.contributor.author | Dincer, Y | |
dc.date.accessioned | 2021-03-06T10:10:15Z | |
dc.date.available | 2021-03-06T10:10:15Z | |
dc.date.issued | 2000 | |
dc.identifier.citation | Akcay T., Dincer Y., Kayali R., Colgar U., Oral E., Cakatay U., "Effects of hormone replacement therapy on lipid peroxides and oxidation system in postmenopausal women", JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A, cilt.59, ss.1-5, 2000 | |
dc.identifier.issn | 0098-4108 | |
dc.identifier.other | av_e9114c35-6a4b-4144-ab5c-ee0564acd46b | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/153164 | |
dc.identifier.uri | https://doi.org/10.1080/009841000157023 | |
dc.description.abstract | A short-term evaluation of 6 months of estrogen therapy on oxidant status in 38 postmenopausal women was conducted. The levels of serum lipid peroxidation products, glutathione (GSH) status, and glutathione-related enzymes were evaluated before and after 6 months of hormone replacement therapy. After 6 months of estrogen treatment there was a significantly increased concentration of thiobarbituric acid-reactive substances (TBARS), which are an end product of lipid peroxidation. This was accompanied by a significant increase in the activity of glutathione peroxidase (GSH-Px). However, the activities of glutathione reductase (GSSG-R) and superoxide dismutase (SOD) were significantly decreased and total protein thiols were reduced. Data suggest that hormone replacement therapy in postmenopausal women is associated with oxidant mechanisms. | |
dc.language.iso | eng | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Mühendislik ve Teknoloji | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Eczacılık | |
dc.subject | ÇEVRE BİLİMLERİ | |
dc.subject | Çevre / Ekoloji | |
dc.subject | Tarım ve Çevre Bilimleri (AGE) | |
dc.subject | KAMU, ÇEVRE VE İŞ SAĞLIĞI | |
dc.subject | Sosyal Bilimler Genel | |
dc.subject | Sosyal Bilimler (SOC) | |
dc.subject | TOKSİKOLOJİ | |
dc.subject | Farmakoloji ve Toksikoloji | |
dc.subject | Meslek Bilimleri | |
dc.subject | Farmasötik Toksikoloji | |
dc.subject | Sosyal ve Beşeri Bilimler | |
dc.subject | Sosyoloji | |
dc.subject | Tarımsal Bilimler | |
dc.subject | Çevre Mühendisliği | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.title | Effects of hormone replacement therapy on lipid peroxides and oxidation system in postmenopausal women | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A | |
dc.contributor.department | , , | |
dc.identifier.volume | 59 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 1 | |
dc.identifier.endpage | 5 | |
dc.contributor.firstauthorID | 124805 | |