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Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells

dc.contributor.authorGEYIK, Filiz
dc.contributor.authorUNALTUNA, Nihan Erginel
dc.contributor.authorCoban, NESLİHAN
dc.contributor.authorYıldırım, Ozlem
dc.date.accessioned2021-03-02T22:34:32Z
dc.date.available2021-03-02T22:34:32Z
dc.date.issued2017
dc.identifier.citationCoban N., GEYIK F., Yıldırım O., UNALTUNA N. E. , "Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells", TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.45, sa.2, ss.118-125, 2017
dc.identifier.othervv_1032021
dc.identifier.otherav_0d779e96-d040-4ee2-b367-dc37b4152a38
dc.identifier.urihttp://hdl.handle.net/20.500.12627/14653
dc.identifier.urihttps://doi.org/10.5543/tkda.2016.82389
dc.description.abstractObjective: Ceramide, the backbone of sphingolipids, is the key component affecting atherosclerotic changes through its important second-messenger role. Previous studies have demonstrated protective role of AMP-activated protein kinase (AMPK) genes in regulating atherosclerosis and hypertension. Ceramide synthase 5 (LASS5 or CERS5) gene has function in de novo synthesis of ceramide, and has indirect effect on AMPK gene. Aim of the present study was to identify role of LASS5 gene in atherosclerosis.
dc.language.isoeng
dc.subjectTıp
dc.subjectKardiyoloji
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCARDIAC ve CARDIOVASCULAR SİSTEMLER
dc.titleInvestigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells
dc.typeMakale
dc.relation.journalTURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume45
dc.identifier.issue2
dc.identifier.startpage118
dc.identifier.endpage125
dc.contributor.firstauthorID93


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