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dc.contributor.authorArioz, Habibi
dc.contributor.authorAdaletli, I
dc.contributor.authorMADAZLı, Rıza
dc.contributor.authorZEYTUN, P
dc.contributor.authorKalyoncu, Ucar
dc.contributor.authorKANDEMIRLI, Sedat Giray
dc.contributor.authorAlici, Davutoglu
dc.contributor.authorOZEL, A
dc.contributor.authorASLAN, M
dc.date.accessioned2021-03-06T07:52:56Z
dc.date.available2021-03-06T07:52:56Z
dc.identifier.citationArioz H., Alici D., KANDEMIRLI S. G. , ASLAN M., OZEL A., Kalyoncu U., ZEYTUN P., MADAZLı R., Adaletli I., "In vivo assessment of placental elasticity in intrauterine growth restriction by shear-wave elastography", European Journal of Radiology, cilt.97, ss.16-20, 2017
dc.identifier.issn0720-048X
dc.identifier.othervv_1032021
dc.identifier.otherav_de50977b-49c1-40ae-9759-f3ef3e2b464f
dc.identifier.urihttp://hdl.handle.net/20.500.12627/146468
dc.identifier.urihttps://doi.org/10.1016/j.ejrad.2017.10.007
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85030830877&origin=inward
dc.description.abstract© 2017 Elsevier B.V.Purpose In this study, we evaluated the placental elasticity in vivo by shear-wave elastography in pregnant women under follow-up for intrauterine growth restriction (IUGR) and compared the elasticity values to normal pregnancies. Material and methods This prospective study included 42 pregnant women with a possible diagnosis of intrauterine growth restriction based on obstetrical grayscale and Doppler ultrasonography and 42 women with a normal pregnancy during the 2nd and 3rd trimester. During follow-up examinations, seven fetuses showed an increased growth and were delivered with a birth-weight above the 10 percentile. However, for statistical purposes we included these seven patients in the IUGR group due to prospective nature of the study. All patients initially underwent obstetrical grayscale and Doppler ultrasonography with measurement of resistivity and pulsatility indices from uterine arteries. Subsequently, elasticity values of the peripheral and central part of the placentas from fetal and maternal surfaces were measured by shear-wave elastography. Following delivery, Apgar scores at 1 st and 5th minute, birth weight were collected. For statistical analysis, Mann-Whitney U test was used. ROC curves were plotted and cut-off values for elasticity values were analyzed. Results Median elasticity values of the central part of the placentas from maternal (28 kPa vs 6 kPa) and fetal sides (21.5 kPa vs 5 kPa) were significantly higher in IUGR pregnancies compared to the control group (p < 0.001). Similarly, median elasticity values of peripheral part of placentas from maternal (22 kPa vs 5.35 kPa) and fetal sides (22.5 kPa vs 5.3 kPa) were significantly higher in IUGR pregnancies compared to the control group (p < 0.001). Conclusion Placental stiffness values are significantly higher in patients with IUGR. Shear-wave elastography can be used as a non-invasive, complementary method to gray-scale and Doppler ultrasound for diagnosing IUGR.
dc.language.isoeng
dc.titleIn vivo assessment of placental elasticity in intrauterine growth restriction by shear-wave elastography
dc.typeMakale
dc.relation.journalEuropean Journal of Radiology
dc.contributor.department, ,
dc.identifier.volume97
dc.identifier.startpage16
dc.identifier.endpage20
dc.contributor.firstauthorID159951


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