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dc.contributor.authorAktuglu, Mehmet Burak
dc.contributor.authorCandan, Gonca
dc.contributor.authorKaraali, Zeynep Ermis
dc.contributor.authorErgen, Arzu
dc.contributor.authorVelet, Mustafa
dc.date.accessioned2021-03-06T07:45:55Z
dc.date.available2021-03-06T07:45:55Z
dc.date.issued2018
dc.identifier.citationKaraali Z. E. , Candan G., Aktuglu M. B. , Velet M., Ergen A., "Toll-Like Receptor 2 (TLR-2) Gene Polymorphisms in Type 2 Diabetes Mellitus", CELL JOURNAL, cilt.20, ss.559-563, 2018
dc.identifier.issn2228-5806
dc.identifier.otherav_ddd19a3c-2312-474a-a1de-a8224c0bd8e8
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/146137
dc.identifier.urihttps://doi.org/10.22074/cellj.2019.5540
dc.description.abstractObjective: Innate immunity factors are associated with type 2 diabetes (T2DM) and its complications. Therefore, T2DM has been suggested to be an immune-dependent disease. Elevated fasting glucose level and higher concentrations of innate immunity soluble molecules are not only related with insulin resistance, but inflammation is also an important factor in beta cell dysfunction in T2DM. Toll-like receptor 2 (TLR-2), which has an important role in inducing innate immune cells, is thought to have suppressive roles on immune responses in T2DM. We therefore aimed to investigate the possible role of TLR-2 del -196-174 and Arg753GIn variants in T2DM pathogenesis.
dc.language.isoeng
dc.subjectTıp
dc.subjectTemel Bilimler
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri
dc.subjectHistoloji-Embriyoloji
dc.subjectTemel Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectHÜCRE BİYOLOJİSİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.titleToll-Like Receptor 2 (TLR-2) Gene Polymorphisms in Type 2 Diabetes Mellitus
dc.typeMakale
dc.relation.journalCELL JOURNAL
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume20
dc.identifier.issue4
dc.identifier.startpage559
dc.identifier.endpage563
dc.contributor.firstauthorID258748


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