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dc.contributor.authorSourer, Ayper
dc.contributor.authorSutcu, Murat
dc.contributor.authorSalman, Nuran
dc.contributor.authorAcar, Manolya
dc.date.accessioned2021-03-05T19:30:51Z
dc.date.available2021-03-05T19:30:51Z
dc.date.issued2017
dc.identifier.citationAcar M., Sutcu M., Salman N., Sourer A., "The Risk of Tuberculosis and TNF-alpha Inhibitors", JOURNAL OF PEDIATRIC INFECTION, cilt.11, 2017
dc.identifier.othervv_1032021
dc.identifier.otherav_cfa68f93-c358-489a-9316-8f2c5941aead
dc.identifier.urihttp://hdl.handle.net/20.500.12627/137296
dc.identifier.urihttps://doi.org/10.5578/ced.201719
dc.description.abstractThe clinical use of TNF-alpha inhibitors have been increasing in the treatment of autoimmune disorders. The most common anti-TNF-alpha agents on clinical use are ethanercept, infliximab and adalimumab. TNF-alpha is an important mediator in the pathogenesis of tuberculosis, therefore the use of TNFAI increases the risk of tuberculosis. Patients who are on anti-TNF alpha treatment should be carefully evaluated for tuberculosis risk before and during therapy. The recommended screening tools are detailed history, physical examination, tuberculin skin test and/or interferon gamma (IFN-gamma) release assay and chest X-Ray every six months.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectPEDİATRİ
dc.titleThe Risk of Tuberculosis and TNF-alpha Inhibitors
dc.typeMakale
dc.relation.journalJOURNAL OF PEDIATRIC INFECTION
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume11
dc.identifier.issue2
dc.contributor.firstauthorID243053


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