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dc.contributor.authorOksuz, Nevra
dc.contributor.authorNeyal, Munife
dc.contributor.authorGoksel, Basak Karakurum
dc.contributor.authorBALAL, MEHMET
dc.contributor.authorSen, Sedat
dc.contributor.authorEKMEKCİ, ÖZGÜL
dc.contributor.authorKaya, Derya
dc.contributor.authorSevim, Serhan
dc.contributor.authorDemirkiran, Meltem
dc.contributor.authorTERZİ, MURAT
dc.contributor.authorYÜCEYAR, AYŞE NUR
dc.contributor.authorTasdelen, Bahar
dc.contributor.authorİDİMAN, EGEMEN
dc.contributor.authorKurtuncu, Murat
dc.contributor.authorBOZ, CAVİT
dc.contributor.authorTUNCEL, DENİZ
dc.contributor.authorKARABUDAK, RANA
dc.contributor.authorSİVA, Aksel
dc.contributor.authorÖZCAN, ABDULCEMAL
dc.date.accessioned2021-03-05T19:17:01Z
dc.date.available2021-03-05T19:17:01Z
dc.identifier.citationSevim S., Demirkiran M., TERZİ M., YÜCEYAR A. N. , Tasdelen B., İDİMAN E., Kurtuncu M., BOZ C., TUNCEL D., KARABUDAK R., et al., "'Is RLS a harbinger and consequence of MS?: Striking results of the 'RELOMS-T' study'", MULTIPLE SCLEROSIS AND RELATED DISORDERS, cilt.42, 2020
dc.identifier.issn2211-0348
dc.identifier.otherav_ce8e5ef4-eee9-4bb8-8ea0-d7d09d366b14
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/136635
dc.identifier.urihttps://doi.org/10.1016/j.msard.2020.102055
dc.description.abstractBackground: Although studies report a high prevalence rate of restless legs syndrome (RLS) among patients with multiple sclerosis (PwMS) ranging from 13.3 to 65.1%, little is known about the causes of this relationship. Methods: To ascertain the prevalence, features and impact of RLS among PwMS a nation-wide, multicenter, prospective and a cross-sectional survey, designed to reflect all of the PwMS throughout Turkey, was conducted in 13 centers. Exploring the relationship of the two conditions could possibly contribute to the understanding of the causes of the high and wide-ranging prevalence rates and the pathophysiology of both diseases. Results: Of the 1068 participants 173 (16,2%) found to have RLS [RLS(+)] and 895 (83,8%) did not [RLS(-)]. Among the RLS(+) 173, all but 8 patients (4,6%) were underdiagnosed in terms of RLS. More than half of the patients with RLS had 'severe' or 'very severe' RLS. The onset of RLS was before or synchronous with the onset of MS in about a half of our patients. Conclusion: We conclude that RLS should be meticulously investigated in PwMS and MS can be a direct cause of RLS at least in part of PwMS. Our data about the timing of the onset of MS and RLS, along with the high prevalence of RLS in PwMS suggest that the pathologic changes in the initial phases of MS can possibly trigger RLS symptoms.
dc.language.isoeng
dc.subjectNöroloji
dc.subjectKLİNİK NEUROLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.title'Is RLS a harbinger and consequence of MS?: Striking results of the 'RELOMS-T' study'
dc.typeMakale
dc.relation.journalMULTIPLE SCLEROSIS AND RELATED DISORDERS
dc.contributor.departmentMersin Üniversitesi , ,
dc.identifier.volume42
dc.contributor.firstauthorID2284150


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