dc.contributor.author | Aktas, Zerrin | |
dc.contributor.author | KAHRAMAN, MEMET VEZİR | |
dc.contributor.author | KAYAMAN APOHAN, NİLHAN | |
dc.contributor.author | Akcakaya, Handan | |
dc.contributor.author | Oncul, Mustafa Oral | |
dc.contributor.author | Yasar, Merve | |
dc.contributor.author | Dal Yontem, Fulya | |
dc.date.accessioned | 2021-03-05T19:05:24Z | |
dc.date.available | 2021-03-05T19:05:24Z | |
dc.identifier.citation | Yasar M., Dal Yontem F., KAHRAMAN M. V. , KAYAMAN APOHAN N., Aktas Z., Oncul M. O. , Akcakaya H., "Polymeric nanoparticles for selective protein recognition by using thiol-ene miniemulsion photopolymerization", JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2020 | |
dc.identifier.issn | 0920-5063 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_cd95a3ee-0706-410a-885c-77f3fa850d12 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/136030 | |
dc.identifier.uri | https://doi.org/10.1080/09205063.2020.1793705 | |
dc.description.abstract | The fabrication of molecularly imprinted nanoparticles (MIP-NPs) specific for myoglobin by using thiol-ene photopolymerization in miniemulsion was described. Allyl derivatives of phenylalanine as a functional monomer was synthesized and copolymerized with acrylic monomersviaminiemulsion polymerization to produce NIP-NPs with approximately 74 nm number average particle diameter. FTIR and(1)H-NMR analysis confirmed the synthesis of functional monomer. MIP-NPs were prepared in the existence of myoglobin as a template protein. Morphological investigations exhibited that the particle size of the MIP-NPs, increased compared to the corresponding NIPs and the mean particle diameter by number was measured as 141 nm with narrow distribution. NIP-NPs that were polymerized without myoglobin were found to have less affinity to the target protein. In addition, the rebinding ability of MIP-NPs was much bigger than that of the corresponding NIPs. ELISA results showed that MIPs interact particularly with the myoglobin and show little affinity for BSA in competitive binding experiments. | |
dc.language.iso | eng | |
dc.subject | Temel Bilimler | |
dc.subject | Mühendislik ve Teknoloji | |
dc.subject | MÜHENDİSLİK, BİYOMEDİKSEL | |
dc.subject | Mühendislik | |
dc.subject | Mühendislik, Bilişim ve Teknoloji (ENG) | |
dc.subject | MALZEME BİLİMİ, BİYOMATERYAL | |
dc.subject | Malzeme Bilimi | |
dc.subject | POLİMER BİLİMİ | |
dc.subject | Kimya | |
dc.subject | Temel Bilimler (SCI) | |
dc.subject | Biyomedikal Mühendisliği | |
dc.subject | Fizikokimya | |
dc.subject | Polimer Karakterizasyonu | |
dc.title | Polymeric nanoparticles for selective protein recognition by using thiol-ene miniemulsion photopolymerization | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | |
dc.contributor.department | Marmara Üniversitesi , , | |
dc.contributor.firstauthorID | 2283971 | |