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Serum procarboxypeptidase A and carboxypeptidase A levels in pancreatic disease

dc.contributor.authorKemik, Ahu Sarbay
dc.contributor.authorPurisa, SEVİM
dc.contributor.authorKemik, Özgür
dc.contributor.authorSumer, Aziz
dc.contributor.authorBegenik, Huseyin
dc.contributor.authorDulger, Ahmet Cumhur
dc.contributor.authorTuzun, Sefa
dc.date.accessioned2021-03-05T19:02:08Z
dc.date.available2021-03-05T19:02:08Z
dc.date.issued2012
dc.identifier.citationKemik Ö., Kemik A. S. , Sumer A., Begenik H., Dulger A. C. , Purisa S., Tuzun S., "Serum procarboxypeptidase A and carboxypeptidase A levels in pancreatic disease", HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.31, ss.447-451, 2012
dc.identifier.issn0960-3271
dc.identifier.otherav_cd58c487-a2bb-4766-bc15-d90aad1ec322
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/135886
dc.identifier.urihttps://doi.org/10.1177/0960327111405864
dc.description.abstractBackground and objectives: To determine the serum levels of procarboxypeptidase A (pro-CPA) and carboxypeptidase A (CPA) in patients with acute and chronic pancreatitis and pancreatic cancer. Materials and methods: Serum samples obtained from 96 patients with acute pancreatitis, 101 patients with chronic pancreatitis, 98 patients with pancreatic cancer and 96 control groups were assayed for biochemical parameters and serum pro-CPA and CPA. Results: Serum pro-CPA and CPA levels were significantly higher in acute and in chronic pancreatic cancer patients compared to control group (p < 0.001). Pancreatic cancer patients had significantly higher serum pro-CPA and CPA levels when compared with acute and chronic pancreatitis cases (p < 0.001). Conclusion: These data prove for increased pro-CPA and CPA levels as a biomarker for the diagnosis of pancreatitis and pancreatic cancer.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmasötik Toksikoloji
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectTOKSİKOLOJİ
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.titleSerum procarboxypeptidase A and carboxypeptidase A levels in pancreatic disease
dc.typeMakale
dc.relation.journalHUMAN & EXPERIMENTAL TOXICOLOGY
dc.contributor.departmentVan Yüzüncü Yıl Üniversitesi , Tıp Fakültesi , Cerrahi Tıp Bilimleri Bölümü
dc.identifier.volume31
dc.identifier.issue5
dc.identifier.startpage447
dc.identifier.endpage451
dc.contributor.firstauthorID60459


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