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dc.contributor.authorDREIFUSS, FE
dc.contributor.authorOZKARA, C
dc.contributor.authorHANSEN, CA
dc.date.accessioned2021-03-05T17:50:00Z
dc.date.available2021-03-05T17:50:00Z
dc.date.issued1993
dc.identifier.citationOZKARA C., DREIFUSS F., HANSEN C., "CHANGES IN RED-BLOOD-CELLS WITH VALPROATE THERAPY", ACTA NEUROLOGICA SCANDINAVICA, cilt.88, ss.210-212, 1993
dc.identifier.issn0001-6314
dc.identifier.otherav_c773c766-be15-4045-b643-9c83475e847b
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/132210
dc.identifier.urihttps://doi.org/10.1111/j.1600-0404.1993.tb04218.x
dc.description.abstractIncrease in the red blood cell mean corpuscular volume (MCV), and mean corpuscular haemoglobin (MCH) values in patients receiving Valproate as mono or polytherapy was noted. To investigate this situation 41 epileptic patients were studied on Valproate alone (Group 1) and 20 patients on Valproate added to another antiepileptic drug (AED), (Group 4), and compared with 19 patients on carbamazepine (CBZ) (Group 2) and 12 patients on phenytoin (PHT), (Group 3). The results showed significant rise in MCV values in Groups 1 and 4. The peripheral blood smear and other tests including reticulocyte counts of the patients with abnormal values ruled out macrocytic anemias. We postulate a generalized effect which is the result of alteration in erythrocyte membrane phospholipids.
dc.language.isoeng
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectKLİNİK NEUROLOJİ
dc.subjectKlinik Tıp
dc.titleCHANGES IN RED-BLOOD-CELLS WITH VALPROATE THERAPY
dc.typeMakale
dc.relation.journalACTA NEUROLOGICA SCANDINAVICA
dc.contributor.department, ,
dc.identifier.volume88
dc.identifier.issue3
dc.identifier.startpage210
dc.identifier.endpage212
dc.contributor.firstauthorID29631


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