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Age-Related Co-Expression of BCOR and BCORL1 mRNA in Acute Myeloid Leukemia

dc.contributor.authorSoysal, Teoman
dc.contributor.authorPercin-Pacal, Ferda
dc.contributor.authorSeflekci, Yusuf
dc.contributor.authorSirma-Ekmekci, Sema
dc.contributor.authorKARAKAŞ, Zeynep
dc.contributor.authorCOŞKUN, Feyza
dc.contributor.authorEMRENCE, Zeliha
dc.contributor.authorAr, Muhlis C.
dc.contributor.authorABACI, Neslihan
dc.contributor.authorÜNÜVAR, Ayşegül
dc.contributor.authorEskazan, Ahmet E.
dc.contributor.authorElverdi, Tugrul
dc.contributor.authorSalihoglu, Ayse
dc.date.accessioned2021-03-05T17:23:28Z
dc.date.available2021-03-05T17:23:28Z
dc.date.issued2020
dc.identifier.citationCOŞKUN F., Percin-Pacal F., EMRENCE Z., Ar M. C. , ABACI N., ÜNÜVAR A., Eskazan A. E. , Elverdi T., Salihoglu A., Seflekci Y., et al., "Age-Related Co-Expression of BCOR and BCORL1 mRNA in Acute Myeloid Leukemia", CLINICAL LABORATORY, cilt.66, ss.1485-1493, 2020
dc.identifier.issn1433-6510
dc.identifier.othervv_1032021
dc.identifier.otherav_c55c9e04-59b9-4118-ac77-d2daa3d1ca0c
dc.identifier.urihttp://hdl.handle.net/20.500.12627/130857
dc.identifier.urihttps://doi.org/10.7754/clin.lab.2020.191119
dc.description.abstractBackground: Acute myeloid leukemia (AML) is an aggressive hematological malignancy caused by a variety of genetic abnormalities and epigenetic dysregulation. The incidence of AML is strongly related to age, with the highest incidence rates being in older adults. The loss of function mutations in BCOR and BCORL1 genes have been identified in AML. BCL6 corepressor (BCOR) and BCL6 corepressor like 1 (BCORL1) are important epigenetic regulators as a member of Polycomb repressive complex 1 (PRC1.1), involved in histone modification processes.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectHealth Sciences
dc.subjectMedical Laboratory Technology
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIBBİ LABORATUVAR TEKNOLOJİSİ
dc.titleAge-Related Co-Expression of BCOR and BCORL1 mRNA in Acute Myeloid Leukemia
dc.typeMakale
dc.relation.journalCLINICAL LABORATORY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume66
dc.identifier.issue8
dc.identifier.startpage1485
dc.identifier.endpage1493
dc.contributor.firstauthorID2250191


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