New urinary antigens as markers in bladder cancer

Abstract

Bladder cancer is one of the most common cancer types in men. Recently, new bladder tumor antigens have been isolated from the urine of bladder cancer patients found positive by histology. In this study, urothelial tumor antigens UBC (Urinary Bladder Cancer) and by the BTA(stat) (Bladder Tumor Antigen) were measured test in urine of 56 patients with bladder cancer, by ELISA and immunochromatographic tests, respectively. A control group of 20 healthy subjects was also taken into the study. UBC levels were significantly higher in 64.3 % of the patients. BTA(stat) test was found positive in 40 % of the patients. We conclude that both tests may help in the diagnosis and follow-up of bladder cancer.