Basit öğe kaydını göster

Detection of DNA single-strand breaks and glutathione in mononuclear blood cells of radiotherapy technicians

dc.contributor.authorOmer, Beyhan
dc.contributor.authorDENIZ, G
dc.contributor.authorDARENDELILER, E
dc.contributor.authorAKKOSE, A
dc.date.accessioned2021-03-05T17:06:25Z
dc.date.available2021-03-05T17:06:25Z
dc.date.issued2002
dc.identifier.citationAKKOSE A., Omer B., DENIZ G., DARENDELILER E., "Detection of DNA single-strand breaks and glutathione in mononuclear blood cells of radiotherapy technicians", ADDICTION BIOLOGY, cilt.7, ss.409-414, 2002
dc.identifier.issn1355-6215
dc.identifier.otherav_c3e7af69-aeba-46fb-b4fc-f327f7c3d7ec
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/129963
dc.identifier.urihttps://doi.org/10.1080/1355621021000006008
dc.description.abstractWe wanted to investigate the effects of gamma radiation on DNA single-strand breaks (SSB) and glutathione (GSH) levels in mononuclear blood cells (MNC) of radiotherapy technicians. DNA SSB in MNC of radiotherapy technicians who use Co-60-gamma source in their works were detected by alkaline filter elution and compared to control subjects. In addition, GSH levels were measured using the enzymatic method in MNC. Blood samples were collected from radiotherapy technicians on Monday and Friday. DNA SSB levels were found to be significantly higher in smoking controls compared to non-smoking controls. Significant increases of 36% and 49% in DNA SSB were detected from Monday to Friday for non-smoking and smoking radiotherapy technicians, respectively. GSH levels were found to be decreased significantly from Monday to Friday. gamma-Radiation resulted in increased DNA SSB levels of MNC in radiotherapy technicians throughout the working week and these breaks have been observed to be repaired at the weekend. Smoking habit caused an additional increase in the SSBs observed in radiotherapy technicians.
dc.language.isoeng
dc.subjectSitogenetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMADDE BAĞIMLILIĞI
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.titleDetection of DNA single-strand breaks and glutathione in mononuclear blood cells of radiotherapy technicians
dc.typeMakale
dc.relation.journalADDICTION BIOLOGY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume7
dc.identifier.issue4
dc.identifier.startpage409
dc.identifier.endpage414
dc.contributor.firstauthorID17312


Bu öğenin dosyaları:

DosyalarBoyutBiçimGöster

Bu öğe ile ilişkili dosya yok.

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster