| dc.contributor.author | Kasim, Veli | |
| dc.contributor.author | Gurol, Ali Osman | |
| dc.contributor.author | Suzergoz, Faruk | |
| dc.date.accessioned | 2021-03-05T16:35:46Z | |
| dc.date.available | 2021-03-05T16:35:46Z | |
| dc.date.issued | 2017 | |
| dc.identifier.citation | Gurol A. O. , Kasim V., Suzergoz F., "Antiproliferative effects of fluorine substitute 3,5-di-tert-butylphenol bearing Schiff bases using CFSE-based cell proliferation assay", CURRENT SCIENCE, cilt.112, ss.619-624, 2017 | |
| dc.identifier.issn | 0011-3891 | |
| dc.identifier.other | av_c1684cec-3bf5-4657-9870-5b2a0e341e75 | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/128356 | |
| dc.identifier.uri | https://doi.org/10.18520/cs/v112/i03/619-624 | |
| dc.description.abstract | The determination of antiproliferative properties of compounds on tumour cells is important for assessment of their efficacy in cancer treatment. CFSE-labelled K562 cells were incubated with doxorubicin and ortho-or para-fluorosubstitute Schiff bases (compounds 1 and 2 respectively). CFSE intensities were analysed using flow cytometry. K562 cells treated with doxorubicin resulted in homogeneous high intensity fluorescence after 96 h of incubation. Schiff bases exhibited antiproliferative effects, but lower than doxorubicin. Our results reveal that CFSE assay can be used for determining in vitro antiproliferative features of anticancer drugs and/or compounds from herbal or chemical sources. | |
| dc.language.iso | eng | |
| dc.subject | Temel Bilimler (SCI) | |
| dc.subject | ÇOK DİSİPLİNLİ BİLİMLER | |
| dc.subject | Doğa Bilimleri Genel | |
| dc.subject | Temel Bilimler | |
| dc.title | Antiproliferative effects of fluorine substitute 3,5-di-tert-butylphenol bearing Schiff bases using CFSE-based cell proliferation assay | |
| dc.type | Makale | |
| dc.relation.journal | CURRENT SCIENCE | |
| dc.contributor.department | İstanbul Üniversitesi , , | |
| dc.identifier.volume | 112 | |
| dc.identifier.issue | 3 | |
| dc.identifier.startpage | 619 | |
| dc.identifier.endpage | 624 | |
| dc.contributor.firstauthorID | 240380 | |
