New diterpenoids from the aerial parts of Salvia pilifera

Abstract

Three new diterpenoids, piliferol (2 alpha,20-dihydroxy-12-oxo-abieta-9(11),13-dien-8,20-ether) (1), salvipiliferol (2 alpha,10 beta-dihydroxy-12-oxo-norabieta-9(11) 13-dien) (2), and piliferalactone (2 alpha,8-dihydroxy-12-oxo-abieta-9(11),13-dien-20-oic acid-8,20-lactone) (3), together with 7 known compounds, ursolic acid, oleanolic acid, betulinic acid, alpha-amyrin, lnpeol, beta-sitosterol, and pectolinarigenin, have been isolated from the aerial parts of an endemic Salvia species, S. pilifera. Their structures were elucidated by spectral (UV, IR, 1D-, and 2D-NMR, and HRMS) methods.