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Ovarian antiproliferative activity directed isolation of triterpenoids from fruits of Eucalyptus camaldulensis Dehnh

dc.contributor.authorKingston, David G. I.
dc.contributor.authorOksuz, Sevil
dc.contributor.authorTopcu, Gulacti
dc.contributor.authorTurkmen, Zeynep
dc.contributor.authorYapar, Gönül
dc.contributor.authorGoren, Ahmet Ceyhan
dc.contributor.authorSchilling, Jennifer K.
dc.date.accessioned2021-03-05T16:02:58Z
dc.date.available2021-03-05T16:02:58Z
dc.date.issued2011
dc.identifier.citationTopcu G., Yapar G., Turkmen Z., Goren A. C. , Oksuz S., Schilling J. K. , Kingston D. G. I. , "Ovarian antiproliferative activity directed isolation of triterpenoids from fruits of Eucalyptus camaldulensis Dehnh", PHYTOCHEMISTRY LETTERS, cilt.4, ss.421-425, 2011
dc.identifier.issn1874-3900
dc.identifier.othervv_1032021
dc.identifier.otherav_beca2238-b51c-400b-aedd-cd6e4fbf5767
dc.identifier.urihttp://hdl.handle.net/20.500.12627/126696
dc.identifier.urihttps://doi.org/10.1016/j.phytol.2011.05.002
dc.description.abstractBioassay-guided fractionation of a methanol extract of the fruits of Eucalyptus camaldulensis Dehnh. with moderate antiproliferative activity afforded the new triterpene, 3 beta-acetoxy-urs-11,13(18)-dien-28-oic acid (1) along with the known triterpenoids 3 beta-hydroxy-urs-11-en-28,13 beta-olide (2), 3 beta-acetoxy-urs-11-en-28,13 beta-olide (3), 3-acetylbetulinic acid (4), oleanolic acid (5), ursolic acid (6), beta-amyrin acetate (7), beta-sitosterol (8) and sitosterol 3-O-beta-D-glucopyranoside (9). Their structures were established on the basis of analysis of their (1)H and (13)C NMR, APT, gHSQC, gHMBC, UV, IR and mass spectral data. The tested triterpenoids (1-7) exhibited weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectBİTKİ BİLİMLERİ
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectKİMYA, TIP
dc.subjectKimya
dc.subjectTemel Bilimler (SCI)
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectTarımsal Bilimler
dc.subjectZiraat
dc.subjectBitki Koruma
dc.subjectFitopatoloji
dc.subjectYaşam Bilimleri
dc.subjectBiyokimya
dc.titleOvarian antiproliferative activity directed isolation of triterpenoids from fruits of Eucalyptus camaldulensis Dehnh
dc.typeMakale
dc.relation.journalPHYTOCHEMISTRY LETTERS
dc.contributor.departmentİstanbul Üniversitesi , Adli Tıp Enstitüsü , Fen Bilimleri Abd
dc.identifier.volume4
dc.identifier.issue4
dc.identifier.startpage421
dc.identifier.endpage425
dc.contributor.firstauthorID202688


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