Analysis of Gastric Myoelectrical Activity in Joint Hypermobility Syndrome

Abstract

Joint Hypermobility Syndrome (JHS) is a common non-inflammatory rheumatologic disease characterized by abnormalities in collagen synthesis in the connective tissue. Various gastrointestinal system (GIS) problems such as dyspepsia, gastroesophageal reflux, and diarrhea may occur related to JHS. Gastric myoelectrical activity is evaluated by a non-invasive technique called electrogastrography (EGG) with cutaneous electrodes placed on the abdominal area. EGG signals are recorded from 12 JHS patients and 12 age and sex matched healthy controls in fasting and fed state with a standard test meal. Normogastria, bradygastria, tachygastria and dominant frequency (DF) parameters of the signals are evaluated. Both fasting and fed state bradygastria rates were higher in JHS group than controls. DF of the JHS group was statistically significantly lower than control group both in fasting and fed states.