Diterpenoids from the roots of Salvia sclarea

Abstract

The roots of Salvia sclarea yielded two triterpenoids, 3-oxo-oleanolic acid, alpha-amyrin, a steroid sitosterol and 12 diterpenoids, two of which are new. The known diterpenoids are ferruginol, salvipisone, microstegiol, candidissiol, 2,3-dehydrosalvipisone, aethiopinone, 1-oxoaethiopinone, salvinolone, cryptojaponol, Delta(7)-manool, and the new compounds are sclareapinone and acetylsalvipisone. The structures were established by spectral data and also by TLC comparison for the known compounds. Copyright (C) 1997 Elsevier Science Ltd.