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Sequence variations of NKX2-5 and HAND1 genes in patients with atrial isomerism.

dc.contributor.authorSayitoglu, Muge
dc.contributor.authorHatirnaz, Ozden
dc.contributor.authorHatemi, Ali Can
dc.contributor.authorSaltik, Levent
dc.contributor.authorCine, Naci
dc.contributor.authorOztunc, Funda
dc.contributor.authorKansiz, Erhan
dc.contributor.authorUnaltuna, Nihan Erginel
dc.contributor.authorVural, Burçak
dc.contributor.authorGulec, Çağrı
dc.date.accessioned2021-03-05T14:42:36Z
dc.date.available2021-03-05T14:42:36Z
dc.date.issued2011
dc.identifier.citationHatemi A. C. , Gulec Ç., Cine N., Vural B., Hatirnaz O., Sayitoglu M., Oztunc F., Saltik L., Kansiz E., Unaltuna N. E. , "Sequence variations of NKX2-5 and HAND1 genes in patients with atrial isomerism.", Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, cilt.11, ss.319-28, 2011
dc.identifier.issn1302-8723
dc.identifier.othervv_1032021
dc.identifier.otherav_b87bae8a-c5b0-46c3-b6b2-07de868905b0
dc.identifier.urihttp://hdl.handle.net/20.500.12627/122756
dc.identifier.urihttps://doi.org/10.5152/akd.2011.083
dc.description.abstractObjective: Atrial isomerism is a congenital disorder, which is characterized by lateralization defects in normally asymmetrical developing organs like the heart. Atrial isomerism is supposed to be caused by molecular defects during early development. The NKX2-5 is a cardiac specific transcription factor, which initiates and regulates downstream transcriptional cascades of cardiogenesis. The HAND1 is another transcription factor expressed in the heart, and it is characterized by an asymmetrical pattern of expression. In this study, we aimed to test whether mutations in NKX2-5 and HAND1 genes play a role in the etiology of atrial isomerism.
dc.language.isoeng
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectKardiyoloji
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectCARDIAC ve CARDIOVASCULAR SİSTEMLER
dc.titleSequence variations of NKX2-5 and HAND1 genes in patients with atrial isomerism.
dc.typeMakale
dc.relation.journalAnadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume11
dc.identifier.issue4
dc.identifier.startpage319
dc.identifier.endpage28
dc.contributor.firstauthorID490


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