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dc.contributor.authorUresin, Y
dc.contributor.authorOzkok, Elif
dc.contributor.authorEroglu, Lütfiye
dc.contributor.authorYildiran, G
dc.contributor.authorGuvener, Bora
dc.date.accessioned2021-03-05T14:04:53Z
dc.date.available2021-03-05T14:04:53Z
dc.date.issued1997
dc.identifier.citationUresin Y., Eroglu L., Yildiran G., Guvener B., Ozkok E., "Protective role of immobilization on ouabain-induced arrhythmias", METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, cilt.19, ss.633-636, 1997
dc.identifier.issn0379-0355
dc.identifier.othervv_1032021
dc.identifier.otherav_b555cc18-50c4-4a68-aab8-c0d6d45a6525
dc.identifier.urihttp://hdl.handle.net/20.500.12627/120748
dc.description.abstractThe effects of the opioid-type stressor; immobilization, on severity of ounbain-induced cardiac arrhythmias and the possible involvement of serum catecholamines were investigated in rats. Immobilization significantly reduced the number of ventricular premature beats and the incidence of ventricular tachycardia episodes. The arterial serum catecholamine levels (A, NA and DA), measured immediately after the stressor application, were increased significicantly and were in negative correlation with the arrhythmia parameters. Both changes were reversed by naloxone (5 mg/kg) treatment after application of immobilization. The effects observed in this study may be attributed to the actions of endogenous opioid peptides released during stress.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.titleProtective role of immobilization on ouabain-induced arrhythmias
dc.typeMakale
dc.relation.journalMETHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
dc.contributor.departmentKocaeli Üniversitesi , ,
dc.identifier.volume19
dc.identifier.issue9
dc.identifier.startpage633
dc.identifier.endpage636
dc.contributor.firstauthorID33245


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