| dc.contributor.author | Soluk Tekkeşin, Merva | |
| dc.contributor.author | Aksakallı, Fatma Nihan | |
| dc.contributor.author | Sinanoğlu, Alper | |
| dc.date.accessioned | 2021-03-05T12:52:14Z | |
| dc.date.available | 2021-03-05T12:52:14Z | |
| dc.identifier.citation | Soluk Tekkeşin M., Sinanoğlu A., Aksakallı F. N. , "Assessment of p53 and Bcl-2 Protein Expressions in Oral Lichen Planus and Oral Squamous Cell Carcinoma", 17th International Congress on Oral Pathology and Medicine Joint Meeting of the British Society for Oral & Maxillofacial Pathology, 23 Eylül 2004 - 30 Mayıs 2016, cilt.119, no.3, ss.191 | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.other | av_af5adcb5-8a3e-4542-9221-f2462be79a17 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/116933 | |
| dc.identifier.uri | http://www.oooojournal.net/article/S2212-4403(14)01091-8/pdf | |
| dc.identifier.uri | https://doi.org/10.1016/j.oooo.2014.07.392 | |
| dc.description.abstract | ObjectiveMalignant transformation is suggested to be a consequence of alterations in cell cycle control, and this potential of oral lichen planus (OLP) is still controversial. The aim of this study was to evaluate the malignant transformation of OLP comparing with oral squamous cell carcinoma (OSCC) by immunohistochemistry.Study DesignBcl-2 and p53 expressions were determined by immunohistochemistry in 100 oral mucosal biopsies including normal oral mucosa (n=20), OLP (n=40) and OSCC (n=40).ResultsThere were no significant differences in p53 and bcl-2 expressions between OLP and OSCC cases. However p53 expression was higher in OLP and OSCC compared to normal epithelium (p<0.05).ConclusionsThe results of this study suggest that the expression of these proteins might be an evidence of the potential of malignant transformation process in OLP. Therefore, there is a need for long term follow-up of patients with OLP to detect any malignant alteration.Keywordslichen planus, bcl-2, p53, oral squamous cell carcinoma | |
| dc.language.iso | eng | |
| dc.subject | Oral Diagnoz ve Radyoloji | |
| dc.subject | Temel Bilimler | |
| dc.subject | Patoloji | |
| dc.subject | Klinik Bilimler | |
| dc.subject | Diş Hekimliği | |
| dc.subject | Sağlık Bilimleri | |
| dc.subject | DİŞ HEKİMLİĞİ, ORAL CERRAHİ VE TIP | |
| dc.subject | Klinik Tıp | |
| dc.subject | Klinik Tıp (MED) | |
| dc.title | Assessment of p53 and Bcl-2 Protein Expressions in Oral Lichen Planus and Oral Squamous Cell Carcinoma | |
| dc.type | Bildiri | |
| dc.contributor.department | İstanbul Üniversitesi , Onkoloji Enstitüsü , Tümör Patolojisi | |
| dc.identifier.volume | 119 | |
| dc.contributor.firstauthorID | 2213356 | |
