BRONCHODILATING EFFECT OF INHALED AND INTRAVENOUS MAGNESIUM-SULFATE (COMPARED WITH AERESOL TERBUTALINE)
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The bronchodilating effect of intravenous magnesium sulfate (MgSO4) was studied in 25 asthmatic patients with mild to moderate bronchial reactivity. Subjects received, in random order, on separate days, 3 days apart, saline (NaCl) and MgSO4 inhalation. Spirometry was recorded on each test day before and 5 minutes after NaCl and MgSO4 inhalation. Neither NaCl nor MgSO4 were found to have a significant effect on spirometric measurements. Three days later the patients were administered with an intravenous infusion of saline placebo and 2 g Of MgSO4. Magnesium sulfate infusion rapidly relieved bronchoconstriction and produced significant improvement in lung function measurements.
- Makale