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Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant

dc.contributor.authorNANE, I
dc.contributor.authorCIFTCI, Hayriye
dc.contributor.authorTURKMEN, A
dc.contributor.authorDemir, EROL
dc.contributor.authorTEFIK, Tzevat
dc.contributor.authorKARADENIZ, MS
dc.contributor.authorOGUZ, FS
dc.contributor.authorAYDIN, F
dc.date.accessioned2021-03-05T12:29:23Z
dc.date.available2021-03-05T12:29:23Z
dc.date.issued2018
dc.identifier.citationCIFTCI H., Demir E., KARADENIZ M., TEFIK T., NANE I., OGUZ F., AYDIN F., TURKMEN A., "Influence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant", RENAL FAILURE, cilt.40, ss.395-402, 2018
dc.identifier.issn0886-022X
dc.identifier.othervv_1032021
dc.identifier.otherav_ad736b4f-c07f-4c12-b821-5482f0716c59
dc.identifier.urihttp://hdl.handle.net/20.500.12627/115719
dc.identifier.urihttps://doi.org/10.1080/0886022x.2018.1489285
dc.description.abstractBackground: There are differences in pharmacokinetic of mycophenolic acid among individuals. The UGT1A9 enzyme is of special interest since it is the main enzyme involved in the glucuronidation of MPA. Single nucleotide polymorphisms in the UGT1A9 gene may be responsible for individual differences in the pharmacokinetics of MPA. The aim of this study was to explain MPA pharmacokinetics in UGT1A9 1399 C > T polymorphisms in Turkish renal transplant patients.
dc.language.isoeng
dc.subjectNephrology
dc.subjectUrology
dc.subjectHealth Sciences
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectNefroloji
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectÜROLOJİ VE NEFROLOJİ
dc.titleInfluence of uridine diphosphate-glucuronosyltransferases (1A9) polymorphisms on mycophenolic acid pharmacokinetics in patients with renal transplant
dc.typeMakale
dc.relation.journalRENAL FAILURE
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume40
dc.identifier.issue1
dc.identifier.startpage395
dc.identifier.endpage402
dc.contributor.firstauthorID161067


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