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Expression of IFITM1 in chronic myeloid leukemia patients

dc.contributor.authorOzcelik, T
dc.contributor.authorSoydan, E
dc.contributor.authorOzcan, M
dc.contributor.authorOzet, GL
dc.contributor.authorIlhan, O
dc.contributor.authorAkyerli, CB
dc.contributor.authorBeksac, M
dc.contributor.authorHolko, M
dc.contributor.authorFrevel, M
dc.contributor.authorDalva, K
dc.contributor.authorOzbek, U
dc.contributor.authorGurman, G
dc.contributor.authorAkan, H
dc.contributor.authorWilliams, BRG
dc.date.accessioned2021-03-05T11:37:15Z
dc.date.available2021-03-05T11:37:15Z
dc.date.issued2005
dc.identifier.citationAkyerli C., Beksac M., Holko M., Frevel M., Dalva K., Ozbek U., Soydan E., Ozcan M., Ozet G., Ilhan O., et al., "Expression of IFITM1 in chronic myeloid leukemia patients", LEUKEMIA RESEARCH, cilt.29, ss.283-286, 2005
dc.identifier.issn0145-2126
dc.identifier.othervv_1032021
dc.identifier.otherav_a90d26e6-fb49-438c-9cb3-9dda2ff5f546
dc.identifier.urihttp://hdl.handle.net/20.500.12627/112946
dc.identifier.urihttps://doi.org/10.1016/j.leukres.2004.07.007
dc.description.abstractWe investigated the peripheral blood gene expression profile of interferon induced transmembrane protein 1 (IFITM1) in sixty chronic myeloid leukemia (CML) patients classified according to new prognostic score (NPS). IFITM1 is a component of a multimeric complex involved in the trunsduction of antiproliferative and cell adhesion signals. Expression level of IFITM1 was found significantly different between the high- and low-risk groups (P = 9.7976 x 10(-11)) by real-time reverse transcription polymerase chain reaction (RT-PCR). Higher IFITM1 expression correlated with improved survival (P = 0.01). These results indicate that IFITM1 expression profiling could be used for molecular classification of CML, which may also predict survival. (C) 2004 Elsevier Ltd. All rights reserved.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectHematoloji
dc.subjectOnkoloji
dc.subjectONKOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectHEMATOLOJİ
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.titleExpression of IFITM1 in chronic myeloid leukemia patients
dc.typeMakale
dc.relation.journalLEUKEMIA RESEARCH
dc.contributor.department, ,
dc.identifier.volume29
dc.identifier.issue3
dc.identifier.startpage283
dc.identifier.endpage286
dc.contributor.firstauthorID174739


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