dc.contributor.author | Emre, M | |
dc.contributor.author | Hanagasi, Haşmet Ayhan | |
dc.date.accessioned | 2021-03-05T11:35:05Z | |
dc.date.available | 2021-03-05T11:35:05Z | |
dc.date.issued | 2000 | |
dc.identifier.citation | Emre M., Hanagasi H. A. , "Evidence-based pharmacological treatment of dementia", EUROPEAN JOURNAL OF NEUROLOGY, cilt.7, ss.247-253, 2000 | |
dc.identifier.issn | 1351-5101 | |
dc.identifier.other | av_a8e2ac71-f2fa-48d1-a448-034c235d9c3d | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/112858 | |
dc.identifier.uri | https://doi.org/10.1046/j.1468-1331.2000.00055.x | |
dc.description.abstract | The current literature on the pharmacological treatment of dementia was reviewed and the strength of evidence for the efficacy of each drug was categorized using an evidence-based approach. Acetylcholinesterase-inhibitors represent the only category of drugs with consistently demonstrable efficacy in well-designed studies of Alzheimer's disease, although the effect is not large. There is a lack of prospective, controlled, randomized studies for most of the nootropics. Epidemiological evidence suggests prophylactic effects of oestrogens and anti-inflammatory agents, and a single large-scale trial suggests that long-term administration of vitamin E or selegiline may be associated with improved outcome in patients with Alzheimer's disease. A number of drugs were reported to be effective in the treatment of non-cognitive symptoms of dementia including classical and atypical neuroleptics, antidepressants and anticonvulsants. The evidence for efficacy, however, is not strong for the majority of these compounds. | |
dc.language.iso | eng | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Nöroloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Sinirbilim ve Davranış | |
dc.subject | NEUROSCIENCES | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KLİNİK NEUROLOJİ | |
dc.title | Evidence-based pharmacological treatment of dementia | |
dc.type | Makale | |
dc.relation.journal | EUROPEAN JOURNAL OF NEUROLOGY | |
dc.contributor.department | , , | |
dc.identifier.volume | 7 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 247 | |
dc.identifier.endpage | 253 | |
dc.contributor.firstauthorID | 125552 | |