dc.contributor.author | Goksel, S | |
dc.contributor.author | Yurdusev, N | |
dc.contributor.author | Dogan, O | |
dc.contributor.author | Ozturk, M | |
dc.contributor.author | Yagci, T | |
dc.date.accessioned | 2021-03-05T11:22:11Z | |
dc.date.available | 2021-03-05T11:22:11Z | |
dc.date.issued | 1996 | |
dc.identifier.citation | Yagci T., Goksel S., Dogan O., Ozturk M., Yurdusev N., "Genomic instability in colorectal cancers in Turkey", INTERNATIONAL JOURNAL OF CANCER, cilt.68, ss.291-294, 1996 | |
dc.identifier.issn | 0020-7136 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_a7d09a9c-9891-4bc4-bb1c-6be6418a49ad | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/112173 | |
dc.description.abstract | Microsatellite instability in a subset of colorectal cancers from North America, Europe and Japan has been reported. We examined 88 colorectal cancers from Turkish patients. Five different microsatellite loci (I mono- and 4 dinucleotide repeat regions) were tested. Eight tumors displayed replication errors (RERs) with at least 2 different markers. Right-sided tumors showed significantly higher frequency of microsatellite instability compared with left-sided tumors. The frequency of RER phenotype was slightly higher in tumors occurring in younger (<50 years old) than in older patients (13% vs. 8%), and there was no association between sex and genomic instability. The frequency of genomic instability in our study group was 9%, whereas the reported frequencies in tumors from other countries varied between 12% and 16%. (C) 1996 Wiley-Liss, Inc. | |
dc.language.iso | eng | |
dc.subject | Onkoloji | |
dc.subject | Sağlık Bilimleri | |
dc.subject | İç Hastalıkları | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ONKOLOJİ | |
dc.title | Genomic instability in colorectal cancers in Turkey | |
dc.type | Makale | |
dc.relation.journal | INTERNATIONAL JOURNAL OF CANCER | |
dc.contributor.department | , , | |
dc.identifier.volume | 68 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 291 | |
dc.identifier.endpage | 294 | |
dc.contributor.firstauthorID | 118093 | |