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Validation of a stopping rule at week 12 using HBsAg and HBV DNA for HBeAg-negative patients treated with peginterferon alfa-2a

dc.contributor.authorJanssen, Harry L. A.
dc.contributor.authorFerenci, Peter
dc.contributor.authorBrunetto, Maurizia R.
dc.contributor.authorLanza, A. Galeota
dc.contributor.authorMessina, Vincenzo
dc.contributor.authorIannacone, Claudio
dc.contributor.authorMassetto, Benedetta
dc.contributor.authorRegep, Loredana
dc.contributor.authorColombo, Massimo
dc.contributor.authorLampertico, Pietro
dc.contributor.authorTabak, Fehmi
dc.contributor.authorCakaloglu, Yilmaz
dc.contributor.authorRijckborst, Vincent
dc.contributor.authorHansen, Bettina E.
dc.date.accessioned2021-03-05T11:08:58Z
dc.date.available2021-03-05T11:08:58Z
dc.date.issued2012
dc.identifier.citationRijckborst V., Hansen B. E. , Ferenci P., Brunetto M. R. , Tabak F., Cakaloglu Y., Lanza A. G. , Messina V., Iannacone C., Massetto B., et al., "Validation of a stopping rule at week 12 using HBsAg and HBV DNA for HBeAg-negative patients treated with peginterferon alfa-2a", JOURNAL OF HEPATOLOGY, cilt.56, ss.1006-1011, 2012
dc.identifier.issn0168-8278
dc.identifier.otherav_a6b3ba88-106e-4f16-b0d8-1f144d898805
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/111475
dc.identifier.urihttps://doi.org/10.1016/j.jhep.2011.12.007
dc.description.abstractBackground & Aims: It was recently demonstrated that none of the hepatitis B e antigen (HBeAg)-negative patients without any serum hepatitis B surface antigen (HBsAg) decline and with <2 log hepatitis B virus (HBV) DNA decline at week 12 of a 48-week peginterferon alfa-2a (PEG-IFN) treatment course achieved a sustained response (SR). We aimed at validating this stopping rule in two independent trials.
dc.language.isoeng
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectGastroenteroloji-(Hepatoloji)
dc.subjectGASTROENTEROLOJİ VE HEPATOLOJİ
dc.titleValidation of a stopping rule at week 12 using HBsAg and HBV DNA for HBeAg-negative patients treated with peginterferon alfa-2a
dc.typeMakale
dc.relation.journalJOURNAL OF HEPATOLOGY
dc.contributor.departmentErasmus University Rotterdam , ,
dc.identifier.volume56
dc.identifier.issue5
dc.identifier.startpage1006
dc.identifier.endpage1011
dc.contributor.firstauthorID40861


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