dc.contributor.author | Guezel, Oezlen | |
dc.contributor.author | Salman, Aydin | |
dc.contributor.author | Ithan, Eser | |
dc.date.accessioned | 2021-03-05T09:40:17Z | |
dc.date.available | 2021-03-05T09:40:17Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Guezel O., Ithan E., Salman A., "Synthesis and antimycobacterial activity of new 2-hydroxy-N-(3-oxo-1-thia-4-azaspiro[4.4]non-4-yl)/(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2,2-diphenylacetamide derivatives", MONATSHEFTE FUR CHEMIE, cilt.137, ss.795-801, 2006 | |
dc.identifier.issn | 0026-9247 | |
dc.identifier.other | av_9efc4dc2-e3b6-478f-966b-f90aed1cab93 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/106758 | |
dc.identifier.uri | https://doi.org/10.1007/s00706-006-0475-3 | |
dc.description.abstract | 2-Hydroxy-2,2-diphenylacetohydrazide (2), cyclic ketones, and mercaptoalkanoic acids were converted into 2-hydroxy-N-(3-oxo-1-thia-4-azaspiro[4.4] non/ [4.5] dee-4-yl)-2,2-diphenylacetamide derivatives (3, 4) in a one pot procedure. Compounds 3 and 4 were tested for in vitro antimycobacterial activity against M. tuberculosis H37Rv. The compounds were found to provide 0-86% inhibition of mycobacterial growth in the primary screen conducted at 6.25 mu g/cm(3). | |
dc.language.iso | eng | |
dc.subject | Temel Bilimler (SCI) | |
dc.subject | Alkoloidler | |
dc.subject | KİMYA, MULTİDİSİPLİNER | |
dc.subject | Kimya | |
dc.subject | Biyokimya | |
dc.subject | Temel Bilimler | |
dc.title | Synthesis and antimycobacterial activity of new 2-hydroxy-N-(3-oxo-1-thia-4-azaspiro[4.4]non-4-yl)/(3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-2,2-diphenylacetamide derivatives | |
dc.type | Makale | |
dc.relation.journal | MONATSHEFTE FUR CHEMIE | |
dc.contributor.department | , , | |
dc.identifier.volume | 137 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 795 | |
dc.identifier.endpage | 801 | |
dc.contributor.firstauthorID | 178770 | |