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dc.contributor.authorBilgic, Başar
dc.contributor.authorKarahan, Esin
dc.contributor.authorAdemoglu, Ahmet
dc.contributor.authorDemiralp, Tamer
dc.contributor.authorBayram, ALİ
dc.date.accessioned2021-03-05T09:33:36Z
dc.date.available2021-03-05T09:33:36Z
dc.identifier.citationBayram A., Karahan E., Bilgic B., Ademoglu A., Demiralp T., "Achromatic temporal-frequency responses of human lateral geniculate nucleus and primary visual cortex", VISION RESEARCH, cilt.127, ss.177-185, 2016
dc.identifier.issn0042-6989
dc.identifier.otherav_9e5ee35e-2c05-4ae5-8d42-cc1b9593500b
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/106366
dc.identifier.urihttps://doi.org/10.1016/j.visres.2016.09.001
dc.description.abstractThe sensitivity of the sensory systems to temporal changes of the environment constitutes one of the critical issues in perception. In the present study, we investigated the human early visual system's dependency on the temporal frequency of visual input using fMRI. Blood oxygen level-dependent (BOLD) responses of the lateral geniculate nucleus (LGN) and primary visual cortex (V1) were investigated in a wide frequency range (6-46 Hz) with fine frequency sampling (13 frequencies). Subject-specific functional-anatomic ROIs were derived from the combination of the anatomic template masks and the functional maps derived from multi-session fMRI analyses across all 13 stimulation conditions. Using functional-anatomic ROIs, average responses of LGN and V1 were calculated for each frequency. The V1 surface area was further parsed into 7 eccentricity sectors to detail central and peripheral responses. LGN's response revealed fluctuations on a background of non-significant decrease of the BOLD response with increasing stimulation frequency, while V1 response displayed similar fluctuations with a global maximum in the range of 8-12 Hz, but a rapid and significant decrease with increasing stimulation frequency especially above 14 Hz. This behavior of V1 response valid for both central and peripheral vision emphasizes that the profound low-pass effect of the visual system to visual input emerges in V1, presumably generated by the intra-cortical circuitry of V1 or projections from extra-striate areas. Besides, the high correlation between LGN and V1 BOLD responses across all visual stimulation frequencies supports the oscillatory tuning in thalamo-cortical interactions as previously claimed in electrophysiological studies. (C) 2016 Elsevier Ltd. All rights reserved.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectNEUROSCIENCES
dc.subjectPsikoloji
dc.subjectTemel Bilimler (SCI)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectCerrahi Tıp Bilimleri
dc.subjectGöz Hastalıkları ve Cerrahisi
dc.subjectSosyal ve Beşeri Bilimler
dc.subjectYaşam Bilimleri
dc.subjectSinirbilim ve Davranış
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectOFTALMOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.titleAchromatic temporal-frequency responses of human lateral geniculate nucleus and primary visual cortex
dc.typeMakale
dc.relation.journalVISION RESEARCH
dc.contributor.departmentBoğaziçi Üniversitesi , ,
dc.identifier.volume127
dc.identifier.startpage177
dc.identifier.endpage185
dc.contributor.firstauthorID39986


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