Strategies for continued successful treatment of Alzheimer's disease: switching cholinesterase inhibitors
Date
2003Author
Grossberg, GT
Emre, M
Farlow, MR
Bullock, R
Potkin, SG
Gauthier, S
Metadata
Show full item recordAbstract
Cholinesterase (ChE) inhibitors represent the standard therapeutic approach to the treatment of Alzheimer's disease (AD). However, a proportion of patients experience lack or loss of therapeutic benefit with an initial agent, or discontinue due to safety/tolerability issues. In many instances, no alternative treatment is offered once the initial agent has been stopped. Thus, for many patients, the total duration of treatment is relatively short in comparison with the chronic nature of AD.
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