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Tumour necrosis factor-alpha gene promoter region-308 and -376 G -> A polymorphisms in Behcet's disease

dc.contributor.authorSARUHAN-DIRESKENELI, G
dc.contributor.authorGul, Ahmet
dc.contributor.authorOZBEK, UĞUR
dc.contributor.authorUYAR, Fatma Aytül
dc.contributor.authorDUYMAZ-TOZKIR, J
dc.date.accessioned2021-03-05T08:45:38Z
dc.date.available2021-03-05T08:45:38Z
dc.date.issued2003
dc.identifier.citationDUYMAZ-TOZKIR J., Gul A., UYAR F. A. , OZBEK U., SARUHAN-DIRESKENELI G., "Tumour necrosis factor-alpha gene promoter region-308 and -376 G -> A polymorphisms in Behcet's disease", CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.21, 2003
dc.identifier.issn0392-856X
dc.identifier.othervv_1032021
dc.identifier.otherav_9a8468da-d1b2-462b-90d7-70f5af17bbc2
dc.identifier.urihttp://hdl.handle.net/20.500.12627/103870
dc.description.abstractObjective. Contribution of HLA-B51 to the genetic susceptibility for Behcet's disease is well documented and recent studies suggest involvement of other genes. Tumour necrosis factor (TNF) genes are located in the vicinity of the HLA-B locus. Polymorphisms in the promoter region of TNF-alpha gene has been found to be associated with altered TNF secretion, and it may have a prominent role in the increased inflammatory responses of Behcet's disease.
dc.language.isoeng
dc.subjectİmmünoloji ve Romatoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectROMATOLOJİ
dc.titleTumour necrosis factor-alpha gene promoter region-308 and -376 G -> A polymorphisms in Behcet's disease
dc.typeMakale
dc.relation.journalCLINICAL AND EXPERIMENTAL RHEUMATOLOGY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume21
dc.identifier.issue4
dc.contributor.firstauthorID50967


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