dc.contributor.author | Hacibekiroglu, M | |
dc.contributor.author | Arisoy, N | |
dc.contributor.author | Sever, L | |
dc.contributor.author | Ozbay, G | |
dc.contributor.author | Caliskan, S | |
dc.date.accessioned | 2021-03-05T07:55:43Z | |
dc.date.available | 2021-03-05T07:55:43Z | |
dc.date.issued | 1996 | |
dc.identifier.citation | Caliskan S., Hacibekiroglu M., Sever L., Ozbay G., Arisoy N., "Urinary N-acetyl-beta-D-glucosaminidase and beta(2)-microglobulin excretion in primary nephrotic children", NEPHRON, cilt.74, ss.401-404, 1996 | |
dc.identifier.issn | 0028-2766 | |
dc.identifier.other | av_9656d3c2-ddb6-4c32-966c-d2756ae916a9 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/101193 | |
dc.identifier.uri | https://doi.org/10.1159/000189442 | |
dc.description.abstract | Enzymuria and low molecular weight proteinuria reflect tubular damage and dysfunction, respectively. We examined urinary N-acetyl-beta-D-glucosaminidase (U-NAG) and beta(2)-microglobulin (U-beta(2)M) excretion in 17 steroid-resistant and 39 steroid-sensitive children with nephrotic syndrome whose glomerular filtration rates were within the normal range. Fourteen healthy children were taken as controls. U-NAG and U-beta(2)M levels did not show a difference between the steroid-resistant and steroid-sensitive groups but were significantly higher in the nephrotic groups compared to the controls (p < 0.0001 and p < 0.01, respectively). In the steroid-sensitive group, U-NAG levels were significantly higher in patients in the relapse phase than in those in remission (p < 0.0001). This finding was also valid for U-beta(2)M excretion, but reached significance only for patients in remission who did not receive steroids (p < 0.01). There was a positive correlation between proteinuria and U-NAG and U-beta(2)M excretion in all patients (r(s) = 0.69, p < 0.001 and r(s) = 0.39, p < 0.001, respectively). In conclusion, massive glomerular proteinuria may cause a marked U-NAG excretion and a moderate urinary U-beta(2)M elevation independent of primary renal disease. | |
dc.language.iso | eng | |
dc.subject | Nefroloji | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ÜROLOJİ VE NEFROLOJİ | |
dc.subject | İç Hastalıkları | |
dc.title | Urinary N-acetyl-beta-D-glucosaminidase and beta(2)-microglobulin excretion in primary nephrotic children | |
dc.type | Makale | |
dc.relation.journal | NEPHRON | |
dc.contributor.department | , , | |
dc.identifier.volume | 74 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 401 | |
dc.identifier.endpage | 404 | |
dc.contributor.firstauthorID | 117976 | |