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Effects of insulin-like growth factor-I and platelet-rich plasma on sciatic nerve crush injury in a rat model

dc.contributor.authorGursoy, Esra Basar
dc.contributor.authorParman, Yesim
dc.contributor.authorKOTAN, Dilcan
dc.contributor.authorNurten, Asiye
dc.contributor.authorZengin, Asli
dc.contributor.authorEmel, Erhan
dc.contributor.authorErgun, Selma Sonmez
dc.date.accessioned2021-03-05T07:36:33Z
dc.date.available2021-03-05T07:36:33Z
dc.date.issued2011
dc.identifier.citationEmel E., Ergun S. S. , KOTAN D., Gursoy E. B. , Parman Y., Zengin A., Nurten A., "Effects of insulin-like growth factor-I and platelet-rich plasma on sciatic nerve crush injury in a rat model", JOURNAL OF NEUROSURGERY, cilt.114, ss.522-528, 2011
dc.identifier.issn0022-3085
dc.identifier.otherav_94af8add-7b7b-46e6-8ed7-1b35312932ca
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/100148
dc.identifier.urihttps://doi.org/10.3171/2010.9.jns091928
dc.description.abstractObject. Local administration of insulin-like growth factor-I (IGF-I) has been shown to increase the rate of axon regeneration in crush-injured and freeze-injured rat sciatic nerves. Local administration of platelet-rich plasma (PRP) has been also shown to have a measurable effect on facial nerve regeneration after transection in a rat model. The objective of the study was to compare the effects of locally administered IGF-I and PRP on the parameters of the Sciatic Function Index (SFI), sensory function (SF), axon count, and myelin thickness/axon diameter ratio (G-ratio) in a rat model of crush-injured sciatic nerves.
dc.language.isoeng
dc.subjectCerrahi Tıp Bilimleri
dc.subjectTıp
dc.subjectNöroloji
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectCERRAHİ
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titleEffects of insulin-like growth factor-I and platelet-rich plasma on sciatic nerve crush injury in a rat model
dc.typeMakale
dc.relation.journalJOURNAL OF NEUROSURGERY
dc.contributor.departmentBezmiâlem Vakıf Üniversitesi , ,
dc.identifier.volume114
dc.identifier.issue2
dc.identifier.startpage522
dc.identifier.endpage528
dc.contributor.firstauthorID24530


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