Plasma and erythrocyte lipid peroxidation in smokers

Abstract

Smoking has been associated with the pathogenesis of many diseases and clinical conditions such as chronic obstructive lung disease, atherosclerosis and cancer. However, free-radical mediated lipid peroxidation has been associated with the pathogenesis of many diseases. Smokers, a group at high risk of cardiovascular disease, are exposed to large quantities of reactive free radicals present in gas and tar phases of tobacco smoke. In the present study, we studied the lipid composition, lipoproteins, lipid peroxides and glutathione in plasma and erythrocyte of smokers and nonsmokers.