Uptake Patterns of Untreated Primary Gastrointestinal Extranodal Lymphomas on Initial Staging F-18-FDG PET/CT and Metabolic Tumor Parameters

Abstract

Objective: Non-Hodgkin's lymphomas arising from tissues other than primary lymphatic sites are classified as primary extranodal lymphomas (PEL). PELs of the gastrointestinal system (PGISL) originate from the lymphatic tissues within the gastrointestinal tract. The prognostic value of F-18-FDG PET/CT in lymphomas is high in terms of both overall survival (OS) and disease-free survival (DFS). Our aim was to investigate the uptake patterns and properties of low-grade and high-grade PGISL on primary staging F-18-FDG PET/CT, as well as the prognostic significance of metabolic tumor parameters in high grade PGISL.