The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey

Author
Vastert, Sebastiaan J.
Kasapcopur, Ozgur
Baris, Ezgi H.
Wulffraat, Nico M.
Frenkel, Joost
Jeyaratnam, Jerold
ter Haar, Nienke M.
Lachmann, Helen J.
Ombrello, Amanda K.
Rigante, Donato
Dedeoglu, Fatma
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Abstract
Background: Withholding live-attenuated vaccines in patients using interleukin (IL)-1 or IL-6 blocking agents is recommended by guidelines for both pediatric and adult rheumatic diseases, since there is a risk of infection in an immune suppressed host. However, this has never been studied. This retrospective, multicenter survey aimed to evaluate the safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade.
URI
http://hdl.handle.net/20.500.12627/93206
https://doi.org/10.1186/s12969-018-0235-z
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