Von Willebrand's disease in German Shepherd Dogs in the Marmara region (Turkey)

Abstract

Plasma von Willebrand factor antigen (vWf:Ag) concentrations were determined for 204 German Shepherd Dogs with the ELISA method using the Asserachrom test kit. Other hematological parameters, in particular platelet number, as well as additional parameters such as buccal mucosa bleeding time (BMBT) were evaluated. The Plasma vWF antigen concentration was found to be significantly reduced in dogs affected with von Willebrand's disease (vWD) while BMBT had increased. Plasma vWf:Ag concentration in all dogs ranged from 0.1 % to 180%.