Disulfiram Implantation in Alcohol Dependency: Influence of Sociodemographic and Clinical Variables on Treatment Response

Abstract

Objective: Psychopharmacological, psychotherapeutic and psychosocial treatment methods are being used in alcohol dependence, which is a frequently occurring psychiatric disorder. In alcohol dependence, promising treatment strategies like naltrexone, acamprosate and topiramate are being tested and numerous research studies have been conducted about these novel drugs in recent years. The administration of disulfiram, which has been used for years, appears to be decreasing. Research on disulfiram implantation, which has been used since the 1950's, had been carried out in 1990's. Our aim with this retrospective study was to investigate the contribution of low cost disulfiram implantation to the treatment of individuals with alcoholism and the influence of sociodemographic and clinical characteristics on treatment response.